规范经皮冠状动脉介入治疗围术期抗生素应用成效分析  

Perioperative use of antibiotics in patients undergoing coronary iIntervention surgery according to specification

作　　者：倪慧[1] 王志军[1] 张丽艳[1] 谢慧娟[1] 干铁儿[1] 

机构地区：[1]浙江省中医院,浙江杭州310006

出　　处：《浙江医学教育》2014年第6期46-48,共3页Zhejiang Medical Education

摘　　要：目的:分析经皮冠状动脉介入(PCI)治疗围手术期规范应用抗生素的成效。方法:回顾性调查2011年1月-12月心血管内科择期行PCI手术患者212例作为未规范组,2012年1月-12月心血管内科对择期行PCI手术规范围手术期抗生素应用的228例作为规范组,对患者术后平均住院日、住院药物费用、抗生素使用情况、术后发热情况进行分析。结果:规范围手术期抗生素应用后,抗生素不合理使用率从97.17%下降至0%;术后住院日由5.21±2.18天下降至3.71±1.49天(P<0.05);住院药物费用从6421.1±2619.6元下降至5857.3±2493.8元(P<0.05);术后发热2组差异无统计学意义(P>0.05)。结论:依据卫生部相关规定规范PCI围术期抗生素应用,能缩短住院周期,减轻患者经济负担,不会增加术后发热发生率。[ Objective] To find out and evaluate perioperative prophylactic application of antibiotics in patients undergoing coronary intervention surgery in our hospital pre and post specification. [Method] A retrospective survey was carried out. 211 patients undergoing coronary intervention during Jan 2011 to Dec 2011 were included in pre- specification group and 228 patients undergoing coronary intervention during Jan 2012 to Dec 2012 were included in post - specification group. The average length of stay, drug cost, the fever post operation and the application of antibiotics were evaluated. [ Result] The pedoperative prophylactic antibiotics application rate reduced from 100% to 0% after specification. The average length of stay post- operation reduced to 3.71 ± 1.49 from 5.21 ± 2.18 pre- specification （ P =0.015） and the drug cost during hospital drop to 5857.3 ± 2493.8 yuan from 6421.1 ± 2619.6 yuan pre- specification （ P =0.032）. The fever post- operation between the two groups was not statistically significant. E Condulion] It is necessary to standard the Antibiotics in Patients Undergoing Coronary Inter- vention according to 〈 implement of the Guiding Principles of Clinical Use of Antibiotics 〉 to shorten the length of stay, light the burden of the patients. Furthermore, it will not increase incidence of fever post- operation.

关 键 词：规范 经皮冠状动脉介入术 围术期 抗生素 

分 类 号：R473.5[医药卫生—护理学]