东莨菪碱贴剂内关穴使用防治腹腔镜胆囊切除术后恶心呕吐的观察  

The observation of scopolamine patch at neiguan acupuncture point against postoperative nausea and vomiting after laparoscopic cholecystectomy

作　　者：王茂华[1] 赵晓蓉[1] 梅艳[2] 

机构地区：[1]泸州医学院附属医院麻醉科,四川泸州646000 [2]泸州医学院附属医院手术室,四川泸州646000

出　　处：《现代医药卫生》2015年第1期19-20,23,共3页Journal of Modern Medicine & Health

基　　金：四川省教育厅及泸州市科技局基金资助课题[14ZB0151;2014-S-45(1/12)]

摘　　要：目的探讨东莨菪碱贴剂内关穴使用对腹腔镜胆囊切除术后恶心、呕吐的影响。方法将择期腹腔镜胆囊切除手术患者280例,随机分为东莨菪碱贴剂内关穴贴剂组(SP6)、东莨菪碱贴剂非穴位贴剂组(S)、安慰剂贴剂内关穴贴剂组(CP6)及安慰剂贴剂非穴位贴剂组(C),每组70例。观察术后恶心、呕吐的次数和程度。结果 SP6组及S组恶心、呕吐的发生率及恶心严重程度均优于CP6组及C组,再次接受止吐药物的百分率也明显少于后两组,差异均有统计学意义(P<0.05)。结论东莨菪碱贴剂内关穴使用能有效缓解腹腔镜胆囊切除术后恶心、呕吐。Objective To approach the effect of scopolamine patch at neiguan acupuncture point against postoperative nausea and vomiting after laparoscopic cholecystectomy. Methods A total of 280 patients with elective laparoscopic cholecystectomy were randomly divided into the scopolamine patch at neiguan acupuncture point（group SP6）,scopolamine patch at nonacupuncture point group（group S）,placebo patch at at neiguan acupuncture point（group CP6）,and placebo patch at non acupuncture point group（group C）,each group of 70 cases. The incidence and severity degree of postoperative nausea and vomiting was observed and analyzed. Results Compared to group S and group CP6,the incidence rate and severity degree of postoperative nausea and vomiting were significantly lower than those in the group SP6,group C. The difference had statistically significance（P〈0.05）. Conclusion The application of the scopolamine patch at neiguan acupuncture point may effectively release the postoper-ative nausea and vomiting after the laparoscopic cholecystectomy.

关 键 词：东莨菪碱 穴 内关 胆囊切除术 腹腔镜/副作用 手术后恶心呕吐 穴位贴敷法 外用药 安慰剂 

分 类 号：R657.4[医药卫生—外科学]