鸭坦布苏病毒感染对鸭T淋巴细胞转化功能的影响  

Effect of Duck Infected with Duck Tembusu Virus on T Lymphocyte Function

作　　者：陈翠腾[1] 苏荣茂 黄瑜[1] 傅光华[1] 程龙飞[1] 陈红梅[1] 万春和[1] 傅秋玲[1] 施少华[1] 林建生[1] 

机构地区：[1]福建省农业科学院畜牧兽医研究所,福建福州350013 [2]福建省畜牧兽医总站,福建福州350003

出　　处：《福建农业学报》2014年第11期1062-1065,共4页Fujian Journal of Agricultural Sciences

基　　金：国家自然科学基金项目(31201936);国家现代农业产业技术体系建设专项(CARS-43);福建省种业创新与产业化工程项目(2014)

摘　　要：以麻鸭为动物模型,测定鸭坦布苏病毒感染后鸭的T 淋巴细胞增殖转化能力.结果显示鸭坦布苏病毒感染的试验组鸭外周血淋巴细胞刺激指数呈先上升后下降再回升的趋势,其中于第3d试验组淋巴细胞刺激指数极显著高于对照组（P〈0.01）,于第5d下降至对照组水平,于第7、15d显著低于对照组（P〈0.05）,于第21d回升至接近对照组水平.以上结果表明,鸭坦布苏病毒感染鸭后7～21d会抑制鸭T 淋巴细胞的增殖转化功能,造成鸭T 淋巴细胞的免疫抑制.In this study,Sheldrake was used as the animal model,and we tested the proliferation of its T lymphocyte after infected by duck Tembusu virus.The result showed that after duck Tembusu virus infection, stimulation index of peripheral blood lymphocyte of test group increased first and then decreased,and recovered again.Lymphocyte stimulation index of test group was significantly (P <0.01)higher than that of control group at 3dpi (day post-infected),and then decreased to the level of control group at 5dpi,and was significantly lower (P <0.05)than that of control group at 7dpi and 15dpi,and then recovered to the level of control group at 21dpi.The result indicated that duck Tembusu virus infection could cause the duck T lymphocyte immune suppression during 7 dpi to 21 dpi.

关 键 词：鸭坦布苏病毒 淋巴细胞增殖 刺激指数 

分 类 号：S852[农业科学—基础兽医学]