朱砂毒性、质量控制与合理使用  

Toxicity, Quality Control, and Reasonable Use of Cinnabaris

作　　者：牛东霞[1] 李西林[1] 柳国斌[2] 丁叶芳 

机构地区：[1]上海中医药大学中药学院,上海201203 [2]上海中医药大学附属曙光医院,上海201203

出　　处：《中国中医药信息杂志》2015年第2期130-132,共3页Chinese Journal of Information on Traditional Chinese Medicine

基　　金：上海市科委中药现代化专项(10DZ1972800)

摘　　要：朱砂作为传统中药,至今应用十分广泛。随着临床实践不断发展,对朱砂的认识也逐渐加深,经历了从"无毒"到"有毒"的过程。目前对朱砂和含朱砂制剂的质量和疗效评价主要以总汞含量为指标,但这会导致其毒性被放大,临床应用的安全性遭到质疑,不良反应案例增多,严重影响到临床的使用。为此,本文就朱砂的临床药效、毒性认识及质量控制等进行综述,为朱砂在中成药中的药用价值评价提供参考。As traditional Chinese herbal medicine, cinnabaris is still widely used in the clinicaltreatment so far. With the further development of clinical practice, the understanding ofcinnabaris is gradually deepening from “non-toxic” to “toxic”. Recently the quality and efficacy ofcinnabaris and pharmaceutical preparation containing cinnabaris are mainly evaluated accordingto the total mercury content, which would lead to the expansion of toxicity of cinnabaris.Therefore, its security is suspected in application and cases with adverse reactions are increasing,which have already created obviously negative impact on its clinical application. This articlereviewed the clinical efficacy, toxicity cognition and quality control of cinnabaris, hoping to providereference for the evaluation of its medicinal value in Chinese patent medicine.

关 键 词：朱砂 毒性 质量控制 综述 

分 类 号：R285.1[医药卫生—中药学]