慢性阻塞性肺疾病高龄患者认知障碍的临床分析  

Clinical Analysis of Cognitive Deficit of Chronic Obstructive Pulmonary Disease Patients

作　　者：章邱东[1] 

机构地区：[1]安徽阜阳市人民医院老年科,干部安徽阜阳236000

出　　处：《中国医药指南》2014年第33期7-8,共2页Guide of China Medicine

摘　　要：目的探讨老年慢性阻塞性肺疾病及其严重程度与认识功能障碍的关系。方法选择阜阳市人民医院干部病房2011年至2013年51例老年慢性阻塞性肺疾病患者,并按照FEV1进行分级。另选择40例为正常对照组。应用蒙特利尔认识评估表(MOCA)评估各组患者的认知障碍程度。并从上述51例中选出20例(个人前后FEV1下降超过10%)一组,分别前后两次应用MOCA评估组内每人认知水平,便于纵向比较。结果正常组与不同程度的慢性阻塞性肺疾病患者认知障碍的发生率均有统计学差异。并且随着FEV1预计值越低,认知障碍的发生率越高。所选同一组患者随着FEV1的下降,其认知障碍的发生率也有所增高,或认知障碍程度有所加重。结论慢性阻塞性肺疾病与认知功能障碍的发病密切相关,且COPD程度越重,认知障碍越明显。Objective To study the chronic obstructive pulmonary disease of senile patients and the relationship between its severity and cognitive deficit. Methods To select 51 cases of the senile patients of chronic obstructive pulmonary disease from 2011 to 2013 in the cadres ward of Fuyang people＇s hospital and to catagorize them according to FEV1 into 40 normal control groups. From the above 51 people select 20 people as a group, respectively before and after application of MOCA score, is advantageous for the longitudinal comparison. Results Statistical difference is shown in the occurence of the cognitive deficit of both chronic obstructive pulmonary disease patients from the normal control groups and patients of various conditons and with the lowering of the expected level of FEV1, the occurence of cognitve deficit increases. The same set of selected patients with FEV1 decline, the incidence of the cognitive function has also been increased. Conclusions Chronic obstructive pulmonary disease is highly related to the occurrence of cognitive deficit and the more severe the level of COPD is the more obvious cognitive deficit.

关 键 词：慢性阻塞性肺疾病 认知障碍 高龄 

分 类 号：R563.8[医药卫生—呼吸系统]