双源CT冠状动脉钙化评分评估冠状动脉狭窄程度的研究  

The Study of Coronary Calcium Score Assessed by Dual-source Computed Tomography Coronary Angiography in the Diagnosis of Coronary Artery Stenosis

作　　者：徐亚琼[1] 胡洋[1] 邓伟[1] 

机构地区：[1]阆中市人民医院,四川阆中637400

出　　处：《中外医学研究》2014年第35期21-23,共3页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:探讨双源CT冠状动脉钙化评分对诊断冠状动脉狭窄的价值。方法:回顾性分析在笔者所在医院2012年6月-2013年12月行双源CT冠状动脉造影检查的84例患者,在DSCT图像中评估钙化积分,以及传统冠状动脉造影Gensini评分,利用ROC工作特征曲线,以传统冠状动脉造影检查结果为参考标准,评估双源CT冠状动脉钙化积分预测冠状动脉管腔显著狭窄的诊断能力。结果:钙化积分与Gensini评分之间存在正相关关系(r=0.718,P<0.001),ROC曲线分析显示,钙化积分最佳阈值为321时,检测冠状动脉狭窄≥50%的敏感度、特异度及曲线下面积分别为85%、77%、0.868。结论:钙化积分对预测冠状动脉中度以上狭窄有很高的价值,可为临床诊断冠心病提供一项可靠的无创检查手段。Objective：To investigate the value of coronary calcium score assessed by dual-source computed tomography coronary angiography in the diagnosis of coronary artery stenosis.Method：The DSCT scanned data of 84 suspected coronary heart disease patients in our hospital from June 2012 to December 2013 were retrospectively analyzed,including CACS of coronary artery CT angiography by dual-source CT and CAG,Gensini score was used to evaluate the degree stenosis of coronary artery.The correlation between the two methods was evaluated using Spearman correlation analysis.With CAG as the reference standard,the capability to predict obvious coronary stenosis was compared using ROC curve.Result：There was a positive association between calcium score and Gensini score（r=0.718,P〈0.001）.Calcium scoring had an acceptable value for diagnose CA stenosis ≥50% with optimal cutoff point of 321,yielding a sensitivity,specificity and the area under the AUC were 85%,77% and 0.868,respectively.Conclusion：Calcium score for predicting coronary artery above moderate stenosis has a high value,for the clinical diagnosis of coronary heart disease and provide a reliable noninvasive method.

关 键 词：双源CT Agatston积分 冠状血管造影术 GENSINI评分 

分 类 号：R541.4[医药卫生—心血管疾病] R816.2[医药卫生—内科学]