老年男性前列腺增生与室间隔增厚的相关性研究  

Correlation between Benign Prostatic Hyperplasia and Interventricular Spetal Thickening in Elderly Male

作　　者：于海迪[1] 陈勇[1] 马勇[1] 袁静[1] 杨菲[1] 

机构地区：[1]江苏省苏北人民医院心功能科,江苏省扬州市225001

出　　处：《医学理论与实践》2014年第22期2961-2963,2971,共4页The Journal of Medical Theory and Practice

摘　　要：目的：探讨良性前列腺增生与室间隔增厚及其危险因素的相关性。方法：收集2012年6月－2014年6月在本院泌尿外科就诊的老年男性良性BPH患者237例，其中室间隔厚度正常组198例，室间隔增厚组39例，详细询问病史，测量身高、体质量，并进行空腹血糖（FBG ）、血脂、血清前列腺特异性抗原测定，分别通过心脏超声测量室间隔厚度、腹部超声测量前列腺体积。首先对其影响因素行单因素及多因素分析，最后建立ROC曲线评估高血压及甘油三酯预测室间隔增厚的价值。结果：与正常组比较，增厚组高血压（HBP）、空腹血糖（FBG）、甘油三酯（TG）、高密度脂蛋白（HDL-C）的差异有统计学意义（均 P＜0．05）；HBP及TG对前列腺患者的室间隔增厚有影响（ORHBP＝3．762，PHBP＝0．044；ORTG ＝2．682，PTG ＝0．008）；HBP联合TG预测室间隔异常的ROC曲线下面积AUC为0．7387，其中95％CI为0．6352～0．8422。结论：TG和 HBP是影响老年前列腺患者室间隔异常的因素，且是预测室间隔异常的较好指标。Objective ：To study the relationship between benign prostatic hyperplasia（BPH） and interventricular spetal thickening in elderly male .Methods ：From June 2012 to June 2014 ,237 consecutively referred patients with BPH were enrolled in this study ,in which 198 cases were isolated benign prostatic hyperplasia ,39 cases were BPH with interventricular spetal thickening .All patients were questioned in detail about history .Blood pressure ,body weight and height were measured .Prostate Specific Antigen （PSA） and fasting blood glucose （FBG） and lipids were assayed in the study . Prostate volume （PV） was detected by abdominal ultrasound and the interventricular spetal thickness was measured by ultrasonic cardiogram .The mean of the factors were compared between the two groups .The receiver operating characteristic （ROC） curves were used for evaluating the sensitivity and specificity of hypertension （HBP） and triglyceride （TG） in predicting the increased thickness of IVS .Results：HBP ,FBG ,TG ,high density lipoprotein （HDL-C） were significantly higher in the interventricular spetal thickness group than in normal group （P〈0 .05） .The increased thickness of IVS was correlated with HBP （OR=3 .762 ,P=0 .044） and TG （OR=2 .682 ,P=0 .008） .Statistically significant differences of HBP and TG were found between the groups with or without increased thickness of IVS .The area under ROC curve of HBP and TG was 0 .738 7 ,95% CI 0.635 2-0.842 2 .Conclusion：HBP and TG are risk factors of increased thickness of IVS in elderly patients with prostatic hyperplasia .And they are accurate predictors of increased thickness of IVS .

关 键 词：良性前列腺增生 室间隔增厚 高血压 甘油三酯 

分 类 号：R697.32[医药卫生—泌尿科学] R541[医药卫生—外科学]