斑马鱼模型及其在血管生成抑制剂筛选中的应用  

The Model of Zebra Fish and Its Application to the Screening of Angiogenesis Inhibitor

作　　者：冯康虎[1] 方鹏飞[2] 张文贤[1] 韩立文[3] 

机构地区：[1]甘肃省中医院,甘肃兰州730050 [2]甘肃中医学院 [3]山东省科学院生物所药物筛选研究室

出　　处：《西部中医药》2014年第12期141-144,共4页Western Journal of Traditional Chinese Medicine

基　　金：甘肃省中医药管理局基金项目(编号GZK-2012-56)

摘　　要：斑马鱼基因与人类高度相似,其模式生物正广泛应用到人体生理和病理的多项研究以及新型药物的筛选中,就目前斑马鱼模型及其在血管生成抑制剂筛选中的应用状况进行阐述。Since there are high genetic similarities between zebra fish and human, the model organisms of zebra fish are widely used to many studies about human physiology and pathology as well as the screening of new drugs, the paper is discussing the model of zebra fish and its application to the screening of angiogenesis inhibitor.

关 键 词：斑马鱼 模型筛选 血管生成抑制剂 抗肿瘤血管生成 

分 类 号：R285.6[医药卫生—中药学]