乙型病毒性肝炎对变应性鼻炎患者皮肤点刺试验的影响  

Influence of Hepatitis B Viral Hepatitis on Skin Prick Test in Patients with Allergic Rhinitis

作　　者：鲍诗平[1] 郭宏伟[2] 刘勇刚[1] 张伟[1] 

机构地区：[1]首都医科大学附属北京佑安医院耳鼻咽喉头颈外科,北京市100069 [2]北京市商业学校

出　　处：《中国全科医学》2014年第33期3985-3987,共3页Chinese General Practice

摘　　要：目的探讨乙型病毒性肝炎对变应性鼻炎患者皮肤点刺试验的影响。方法回顾性分析2011年7月—2012年11月至我院耳鼻咽喉头颈外科门诊就诊的有变应性鼻炎病史及体征阳性患者191例标准皮肤点刺试验结果 (43例合并乙型病毒性肝炎病史),分析乙型病毒性肝炎对变应性鼻炎患者皮肤点刺试验的影响。结果皮肤点刺试验总阳性率为72.25%(138/191),合并乙型病毒性肝炎患者阳性率为81.40%(35/43),未合并乙型病毒性肝炎患者阳性率为69.59%(103/148),差异无统计学意义(χ2=2.314,P=0.128)。结论乙型病毒性肝炎引起的自身免疫反应不影响变应性鼻炎的诊断和变应原检测,血清IgE检测在该类人群中具有临床应用价值,其检测结果可靠,能够提供变应原检测的真实信息。Objective To investigate the influence of hepatitis B viral hepatitis on skin prick test in patients with allergic rhinitis. Methods 191 samples（ 43 cases were combined with viral hepatitis B） of skin prick test in the Department of Otolaryngology Head and Neck Surgery in our hospital from July 2011 to November 2012 were analyzed retrospectively. The influence of viral hepatitis B on skin prick test of patients with allergic rhinitis was analyzed. Results The overall positive rate of skin prick test was 72. 25%（ 138 /191）,and the positive rate of skin prick test was 81. 40%（ 35 /43） for patients with viral hepatitis B and69. 59%（ 103 /148） for patients without it. The difference was not statistically significant（ χ^2= 2. 314,P = 0. 128）. Conclusion The autoimmune response caused by viral hepatitis B does not affect the diagnosis and allergen detection of allergic rhinitis. Serum IgE detection has reliable clinical value in the group and can provide reliable information of the allergen.

关 键 词：鼻炎 变异性 季节性 诊断 皮肤点刺试验 肝炎 乙型 慢性 

分 类 号：R76[医药卫生—耳鼻咽喉科]