新型8-位取代腺苷衍生物的合成  

Synthesis of Novel 8-Substituted Adenosine Derivatives

作　　者：张逸伟[1] 吴泽秋 林东恩[1] 廖能[1] 

机构地区：[1]华南理工大学化学与化工学院,广东广州510640

出　　处：《合成化学》2014年第6期789-792,共4页Chinese Journal of Synthetic Chemistry

摘　　要：以腺苷为原料,经溴代反应制得8-溴-腺苷(2);2与单取代芳酰基哌嗪经取代反应合成了5个新型的8-位取代腺苷衍生物,其结构经1H NMR和ESI-MS表征。Five novel 8-substituted adenosine derivatives were synthesized by the substitution reaction of N-aroyl-piperazine with 8-bromoadenosine prepared by bromination reaction from adenosine. The structures were characterized by^1 H NMR and ESI-MS.

关 键 词：腺苷 哌嗪 合成 

分 类 号：O629.7[理学—有机化学]