电针环跳、委中穴对兔腰椎间盘突出症的影响  

Effect of Electroacupuncture at Huantiao and Weizhong Point on Rabbits with Lumbar Interver Tebral Disc Protrusion

作　　者：封迎帅[1] 刘百祥[1] 张亮[2] 易受乡[2] 阳大为[1] 

机构地区：[1]湖南省人民医院中医科针灸室,湖南长沙410005 [2]湖南中医药大学,湖南长沙410007

出　　处：《湖南中医药大学学报》2014年第11期53-56,共4页Journal of Hunan University of Chinese Medicine

基　　金：湖南省中医药管理局资助项目(201378)

摘　　要：目的观察电针环跳、委中穴对腰椎间盘突出症(lumbar intervertebral disc protrusion,LIDP)家兔步态功能﹑髓核组织中肿瘤坏死因子(tumor necrosis factor-α,TNF-α)和白细胞介素-6(interleukin-6,IL-6)含量的影响。方法将40只健康新西兰兔随机分为4组,即空白组、LIDP模型组、电针穴位组和电针非穴对照组。自制的LIDP家兔病理模型造模器造家兔LIDP病理模型,采用Siegal法记录步态功能,酶联免疫吸附法测定髓核组织中TNF-α、IL-6含量。结果电针穴位组可改善家兔的步态功能,降低LIDP家兔髓核组织中TNF-α、IL-6的含量,与LIDP模型组、电针非穴对照组比较有显著性差异(P<0.01)。结论通过降低髓核组织中TNF-α、IL-6等炎症因子含量减轻炎症反应可能是电针环跳、委中穴治疗LIDP的作用机制之一。Objective To observe the effects of electroacupuncture at Huantiao and Weizhong point on the walking function, tumor necrosis factor-α （TNF-α） and interleukin-6 （IL-6） in rabbits with lumbar intervertebral disc protrusion （LIDP）. Methods Forty healthy New Zealand rabbits were randomly divided into the blank, LIDP model, electroaeupuncture at point and electroacupuncture at non-point groups. The LIDP pathologic models were induced by the self-manufactured instrument, the walking functions of the rabbits were recorded by Siegal method, the contents of TNF-α and IL -6 were measured by ELISA method. Results The walking function of rabbits in electroacupuncture at Huantiao and Weizhong points group were improved, the contents of TNF-α and IL-6 in nuclei pulpous significantly decreased. Compared with model and non-point control groups, the electroacupuncture group had significant differences （P〈0.O1）. Conclusion One ofthe mechanisms of electroacupuncture at Huantiao and Weizhong point for LIDP treatment could be by decreasing the TNF-α and IL-6.

关 键 词：腰椎间盘突出症 电针 环跳穴 委中穴 肿瘤坏死因子-α 白细胞介素-6 家兔 

分 类 号：R246.2[医药卫生—针灸推拿学]