第二代三唑类抗真菌药物的研究进展  

Research progress on the second generation of triazole antifungal drugs

作　　者：郭天阳[1] 杜安通 杨雅骊[2,3] 潘炜华[2,3] 

机构地区：[1]第二军医大学学员旅临床二队,上海200003 [2]上海长征医院皮肤病与真菌病研究所 [3]上海长征医院皮肤科

出　　处：《世界临床药物》2014年第12期715-718,共4页World Clinical Drug

基　　金：欧莱雅基金(S2014111106);国家973项目(2013CB531601);重大传染病防治科技重大专项(2013ZX10004612);上海市科委基金资助项目(14DZ2272900)

摘　　要：侵袭性真菌病的发病率和病死率逐年上升,新型抗真菌药物的研究和开发也越来越受到重视,尤其是三唑类抗真菌药物。本文综述国内外近期关于第二代三唑类抗真菌药物的研究进展,以期为未来临床真菌病的治疗及新药研发提供新的思路。Recent years, the morbidity and mortality of invasive fungal disease are increased year by year. The research and development of new antifungal drugs has been paid more and more attention, especially in the area of triazole antifungal drugs. This review describes the recent research progress on the second generation of triazole antifungal drugs to provide new ideas for clinical management and future new drug development.

关 键 词：抗真菌药物 三唑类 侵袭性真菌病 

分 类 号：R978.5[医药卫生—药品]