系列烃基和烷氧基取代芳胺的合成方法研究  

Synthesis of Aryl,Alkyl and Methyoxyl-stituted Anlines

作　　者：刘欢[1] 申东升[1] 刘丰收[1] 刘睿智[1] 张新生[1] 

机构地区：[1]广东药学院医药化工学院,广东广州610005

出　　处：《广东化工》2014年第23期28-30,共3页Guangdong Chemical Industry

摘　　要：研究合成芳胺化合物的新路线。以简单芳胺为原料,通过铃木偶联法和傅——克烷基化法,制备一系列不同芳基和烷基取代的芳香有机胺,合成了8个目标产物。这些化合物经核磁共振氢谱和碳谱表征其结构。结果表明该合成路线经济可靠,改进后的实验操作条件简单易行。To investigate new routes for the synthesis of 2,4,6-trisubstituted anlines. A series of Aryl and alkyl anlines were synthesized via Suzuki coupling and Fridel-Crafts reaction. The structures of title compounds were confirmed by H-NMR and C-NMR analyses. The improved procedure has the advantage of low costing of starting material and the convenient simple route, which is suitable for large scale of production.

关 键 词：芳胺 铃木偶联 傅-克烷基化 

分 类 号：O625.63[理学—有机化学]