术前使用甲氨蝶呤治疗Ⅰ型剖宫产疤痕妊娠的疗效分析  

Analysis of therapeutic effect of methotrexate before operation on Cesarean scar pregnancy patients

作　　者：曹映华[1] 姚颖杰[1] 

机构地区：[1]昆明市妇幼保健院妇二科腔镜中心,云南昆明650031

出　　处：《云南医药》2014年第6期638-641,共4页Medicine and Pharmacy of Yunnan

摘　　要：目的探讨剖宫产疤痕妊娠（Cesarean scar pregnancy,CSP）行宫腔镜保守性手术联合术前使用甲氨蝶呤MTX的可行性及安全性。方法我院2009年3月至今收治剖宫产瘢痕妊娠患者73例,入院时根据超声检查结果分为Ⅰ型CSP,Ⅱ型CSP。其中Ⅰ型CSP 44例,将该44例患者随机分为2组,A组22例术前给予甲氨蝶呤50~75mg静脉注射,B组22例术前不使用甲氨蝶呤,直接行宫腔镜下清宫或电切环切除妊娠物。结果 A组术中出血量及手术时间较B组有明显差异,2组患者均保留生育功能治愈出院。结论宫腔镜保守性手术术前使用甲氨蝶呤治疗Ⅰ型剖宫产疤痕妊娠具有创伤小、康复快的优点,值得推广。Objective To evaluate the feasibility and safety of methotrexate before hysteroscopic conservative operation on cesarean scar pregnancy patients. Methods 44 type Ⅰ cesarean scar pregnancy patients from our hospital were randomly divided into two groups. Group A had intravenous 50-75 mg injected methotrexate before operation, while group B was solely treated with hysteroscopic conservative operation. The parameters of operation result were analyzed with independent samples t-test. Results Compared with group B, bleeding volume during operation and operation duration of group A were significantly reduced. Conclusion It is effective and micro-traumatic to use of methotrexate before Hysteroscopic conservative operation on type Ⅰ Cesarean scar pregnancy patients. This treatment is worth of popularizing.

关 键 词：宫腔镜手术 甲氨蝶呤 剖宫产疤痕妊娠 

分 类 号：R714.22[医药卫生—妇产科学]