生物电阻抗断层成像技术及其临床研究进展  

Advancements in Electrical Impedance Tomography and Its Clinical Applications

作　　者：徐灿华[1] 董秀珍[1] 

机构地区：[1]第四军医大学生物医学工程学院,西安710032

出　　处：《高电压技术》2014年第12期3738-3745,共8页High Voltage Engineering

基　　金：国家自然科学基金(50337020;50937005;51207161);国家科技支撑计划(2011BAI08B13)~~

摘　　要：生物电阻抗断层成像技术(EIT)是一种无创无放射损伤的功能成像技术。它通过体表电极测量得到的信号重构出内部电阻抗或电阻抗变化的分布。EIT首次出现于20世纪80年代,经过30多年的发展,其基础理论、信息采集、图像重构等方面已得到较大完善,并已过渡到临床研究阶段。该技术在乳腺癌检测成像、腹部脏器功能监测成像、呼吸功能监测成像、脑功能成像等领域得到了广泛关注和快速发展。为此,简述了生物EIT的发展状况,重点介绍了最新的相关临床应用,并提出了有关研究所面临的难点和挑战。Electrical impedance tomography（EIT） restructures the distributions of internal impedance or its change using the signals obtained by electrode measurements on the surface of body, which makes it a non-invasive, non-radiation-injury functional imaging technique. First appearing in the early 1980 s, EIT has been greatly improved in basic principles, data measuring, and image reconstruction, etc after development for more than 30 years, and has successfully reached the verge of clinical applications now. Specifically, EIT has gotten wide attention and rapid development in the fields of breast cancer imaging detection, abdominalorgan functional imaging monitoring, pulmonary perfusion imaging monitoring, and brain functional imaging monitoring, and so on. To this end, we described the recent developments of EIT, especially the newest clinical applications, and proposed the difficulties and challenges of the technology.

关 键 词：电阻抗断层成像 信息采集 图像重构 乳腺癌检测 脏器功能监测 呼吸功能监测 脑功能监测 

分 类 号：R310[医药卫生—基础医学]