狼疮肾炎的药物治疗进展  

Advances in Drug Therapy for Lupus Nephritis

作　　者：李海端[1] 李建华[2] 

机构地区：[1]兰州大学第一临床医学院,兰州730000 [2]兰州大学第一医院肾病科,兰州730000

出　　处：《医学综述》2014年第24期4514-4516,共3页Medical Recapitulate

摘　　要：狼疮肾炎是系统性红斑狼疮累及肾脏所引起的一种免疫复合物性肾炎,是最常见的继发性肾小球疾病。近年来,随着对狼疮肾炎发病机制的研究及肾活检的应用,狼疮肾炎的治疗已取得了可观的效果,狼疮肾炎患者的生存率已显著提高,但是由于狼疮肾炎存在复发及治疗过程中应用各种免疫抑制剂所引起的不良反应,狼疮肾炎的治疗仍存在挑战。该文就狼疮肾炎的药物治疗进展予以综述。Lupus nephritis is a kind of immune complex nephritis caused by systemic lupus erythemato- sus（SLE） ,and it is the most common secondary glomerular disease. In recent years,as the study on the pathogenesis of lupus nephritis and the application of the renal biopsy develops, survival rate of patients with lupus nephritis patient has been improved significantly. However, given the recurrence of lupus nephritis and side effects caused by various immunosuppressive agents in the process of treatment, the treatment for lupus nephritis still remains a challenge. Here is to make a review of the advances in drug therapy for lupus nephritis.

关 键 词：狼疮肾炎 治疗 新型药物 

分 类 号：R593.242[医药卫生—内科学]