六君祛痰解毒汤防治消化道肿瘤术后化疗不良反应及复发转移临床观察  

Clinical Observation of Liujun Qutan Jiedu Decoction Prevention and Treatment of Adverse Reactions and Recurrence and Metastasis after Digestive Tract Tumor Postoperative Chemotherapy

作　　者：陈华圣 王树槐 

机构地区：[1]扬州大学临床医学院,江苏扬州225001

出　　处：《中医学报》2014年第12期1705-1707,共3页Acta Chinese Medicine

基　　金：江苏省高校自然科学研究项目(编号:06KJB360131)

摘　　要：目的：观察六君祛痰解毒汤对术后化疗后消化道肿瘤患者不良反应及复发转移的影响。方法：选取 30例消化道肿瘤患者作为研究对象，均于化疗结束后口服六君祛痰解毒汤，２～３个月后观察患者临床症状、卡氏评分、外周血象及相关肿瘤抗原变化情况，并对六君祛痰解毒汤进行加减，长期口服，观察 30个月内肿瘤转移情况。结果：与治疗前比较，多数患者不良反应的临床症状消失或显著改善，卡氏评分和外周血象明显提升，相关肿瘤标志物水平明显下降或略有下降，30个月内未增加转移病例数。结论：六君祛痰解毒汤可减轻消化道肿瘤患者术后化疗后的不良反应，提高患者的生存质量，具有较好的防止消化道恶性肿瘤术后化疗后复发转移的作用。Objective： To observe the influence of Liujun Qutan Jiedu Decoction prevention and treatment of adverse reactions and recurrence and metastasis after digestive tract tumor postoperative chemotherapy. Methods： 30 patients with digestive tract cancer patients as the research object,and they were given oral administration of Liujun Qutan Jiedu Decoction after chemotherapy,and clinical symptoms,Karnofsky score changes,peripheral blood and tumor associated antigen were observed after 2- 3 months. Addition and subtraction Liujun Qutan Jiedu Decoction,long-term oral,and tumor metastasis was observed in 30 months. Results： Compared with before treatment,clinical symptoms of the adverse reaction of the majority of patients were disappeared or improved significantly,Karnofsky score and peripheral hemogram were improved obviously and the related tumor marker levels were significantly decreased or decreased slightly,without increasing the number of cases of metastasis within 30 months. Conclusion： Liujun Qutan Jiedu Decoction can reduce the adverse reaction of chemotherapy of patients with gastric cancer after,improve the life quality of patients,which has good prevention of recurrence and metastasis after digestive tract tumor postoperative chemotherapy.

关 键 词：六君祛痰解毒汤 消化道肿瘤 术后 化疗后 不良反应 复发转移 

分 类 号：R273.35[医药卫生—中西医结合]