2013年217例药品不良反应报告分析  

Adverse Drug Reactions in 2013: Analysis of 217 Cases

作　　者：宋锦飞[1] 徐琳[1] 孙光春[1] 

机构地区：[1]复旦大学附属上海市第五人民医院药剂科,上海200240

出　　处：《中国医院用药评价与分析》2014年第12期1126-1129,共4页Evaluation and Analysis of Drug-use in Hospitals of China

摘　　要：目的:了解复旦大学附属上海市第五人民医院(以下简称"我院")药品不良反应(ADR)的发生情况,以促进临床合理用药。方法:回顾性调查2013年我院收集的217例ADR报告,从患者的年龄、性别、药品种类、给药途径等方面进行统计、分析。结果:217例ADR中,男女患者比例为0.7∶1.0;≥60岁患者78例(占35.94%);静脉给药147例(占67.74%),口服给药59例(占27.19%);抗感染药致ADR 119例,居首位;ADR临床表现主要为皮肤及其附件损害(80例,占36.87%)。结论:应加强医院ADR监测工作,合理、规范使用抗感染药,避免或减少严重的ADR发生。OBJECTIVE：To investigate the characteristics of adverse drug reaction （ ADR ） in Shanghai Fifth People-s Hospital Affiliated to Fudan University （ hereinafter referred to as “our hospital“） so as to promote clinical rational use of drug. METHODS：217 ADR cases collected in our hospital during 2013 were analyzed statistically in terms of patients-age and gender, drug types and route of administration etc. RESULTS：The 217 ADR cases occurred in male/female ratio of 0.7∶ 1; 78 cases （ 35.94%） aged ≥60 years; 147 cases （ 67.74%） were induced via intravenous injection;59 cases（27.19%） were induced by oral drugs;the anti-infective drugs ranked the first in terms of ADR incidence; 80 cases （ 36.87%） manifested as lesions of skin and its appendants. CONCLUSIONS： It is important to strengthen ADR monitoring in hospital and achieve rational and standard use of anti-infective drugs so as to avoid or reduce the occurrence of severe ADR.

关 键 词：药品不良反应 临床表现 抗感染药 分析 

分 类 号：R969.3[医药卫生—药理学]