达标心率对缺血型心肌病和扩张型心肌病患者的影响  

The Influence of Standard Heart Rate on Patients with ICM and DCM

作　　者：李丹花[1] 金强松 赵晓燕[1] 

机构地区：[1]郑州大学第一附属医院心血管内科,河南郑州450052

出　　处：《医学与哲学（B）》2014年第12期36-38,共3页Medicine & Philosophy(B)

摘　　要：为观察达标心率对缺血型心肌病(ICM)和扩张型心肌病(DCM)患者预后的影响,所有入选ICM和DCM患者均给予常规抗心力衰竭药物及β受体阻滞剂(β-b)治疗,使心率维持于55次/分~60次/分,观察随访1年时的病死率、再入院率、舒张末期左室内径(LVEDd)、左室射血分数(LVEF)、氨基末端脑利钠肽前体(NT-proBNP)水平来评估二者的预后。结果显示,随访结束时ICM患者较DCM患者再入院率低(P=0.037),LVEDd低(P=0.034),LVEF高(P=0.028),收缩压高(P=0.029);对于ICM患者,随访结束时较出院时LVEDd低(P=0.047),LVEF高(P=0.018),收缩压高(P=0.042)。因此,心率达标对ICM患者有助于改善预后,对DCM患者改善不明显,ICM患者心率达标时获益更大。In order to observe the influence of standard heart rate on prognosis in patients with ICM and DCM,all the ICM and DCM patients were given regular anti-HF drugs andβ-blocher,keeping the heart rate at 55bpm^60bpm.By observing the mortality rate,readmission rate,left ventricular end-diastolic dimension（LVEDd）,left ventricular ejection fraction（LVEF）,N-terminal proBNP（NT-proBNP）after one year to evaluate their prognosis.The outcomes were that,at the end of follow-up,the ICM patients had lower readmission rate（P=0.037）,lower LVEDd（P=0.034）,higher LVEF（P=0.028）and higher systolic pressure（P=0.029）than DCM patients.As to the ICM patients at the end of follow-up,it had lower LVEDd（P=0.047）,higher LVEF（P=0.018）and higher systolic pressure（P=0.042）than discharged.So,as to ICM patients,standard heart rate was benefit to improving the prognosis,but it was not significant about DCM patients.The ICM patients had more profits than DCM patients.

关 键 词：达标心率 缺血型心肌病 扩张型心肌病 预后 

分 类 号：R542.2[医药卫生—心血管疾病]