斑点追踪技术定量评价慢性肺源性心脏病患者右心室功能  

Function of Right Ventricle in Patients with Chronic Pulmonary Heart Disease Quantitatively Assessed by Speckle Tracking Echocardiography

作　　者：张佳怡[1] 高静[1] 吴存刚[1] 葛丽丽[1] 李玉宏[1] 

机构地区：[1]辽宁医学院附属第一医院超声科,辽宁锦州121000

出　　处：《医学与哲学（B）》2014年第12期39-41,共3页Medicine & Philosophy(B)

摘　　要：应用斑点追踪技术(STE)定量评价慢性肺源性心脏病患者右心室功能的改变。在我院明确诊断为慢性肺源性心脏病患者39例作为病例组,健康体检人员30例作为对照组。应用STE测量右心室收缩期峰值应变率(SRs)、舒张早期峰值应变率(SRe)、舒张晚期峰值应变率(SRa),计算舒张早期峰值应变率与舒张晚期峰值应变率的比值(SRe/SRa);测量三尖瓣环游离壁舒张早期运动速度峰值(Ea)、舒张晚期运动速度峰值(Aa)并计算其比值(Ea/Aa);计算右心室面积变化率(RVFAC)。病例组RVFAC、Ea/Aa、SRs、SRe、SRa、SRe/SRa均低于对照组(P<0.05)。SRs与RVFAC呈显著正相关(r=0.725,P<0.001)。SRs、RVFAC与PASP呈显著负相关(r1=-0.695,r2=-0.664,P<0.001)。SRe/SRa与Ea/Aa呈显著正相关(r=0.701,P<0.001)。慢性肺源性心脏病患者右心室收缩和舒张功能减低。STE可以定量评价慢性肺源性心脏病患者右心室功能的改变。Speckle tracking echocardiography（STE）is adopted in this study to quantitatively evaluate the function＇s changes of right ventricle in patients with chronic pulmonary heart disease.A total of 39 patients were diagnosed with chronic pulmonary heart disease as case group.A total of 30 healthy people were selected as control group.Measuring peak systolic strain rate（SRs）、peak early-diastolic strain rate（SRe）、peak late-diastolic strain rate（SRa）of right ventricle with STE and calculating the ratio of peak early-diastolic strain rate and peak late-diastolic strain rate（SRe/SRa）;Measuring peak early-diastolic velocity of the tricuspid annulus（Ea）、peak late-diastolic velocity of the tricuspid annulus（Aa）and calculating the ratio（Ea/Aa）;Calculation right ventricle fractional area change（RVFAC）;Case group compared with control group：RVFAC,Ea/Aa,SRs,SRe,SRa,SRe/SRa decreased（P〈0.05）.SRs were positively correlated with RVFAC（r=0.725,P0.001）.SRs,RVFAC were negatively correlated with PASP（r1 =0.695,r2 =0.664,P0.001）.SRe/SRa was positively correlated with Ea/Aa（r=0.701,P0.001）.Both the systolic and diastolic function of right ventricle decreased in patients with chronic pulmonary heart disease.STE could quantitatively evaluate right ventricle function＇s changes in patients with chronic pulmonary heart disease.

关 键 词：慢性肺源性心脏病 肺动脉高压 斑点追踪技术 

分 类 号：R541.5[医药卫生—心血管疾病] R445.1[医药卫生—内科学]