天保宁对高血压引起动脉粥样硬化的疗效观察  

Observation of the curative effect of taponing on hypertension-induced atherosclerosis

作　　者：张强[1] 张伟珍[1] 

机构地区：[1]上海中医药大学附属龙华医院ICU,上海市200032

出　　处：《老年医学与保健》2014年第6期433-436,共4页Geriatrics & Health Care

基　　金：上海市中西医结合学会科研基金项目（zxyk-1233）

摘　　要：目的 通过对TC、HDL、LDL等临床指标比较和斑块积分、动脉硬化指数及中医证侯积分的评价,观察天保宁对高血压合并颈动脉粥样硬化作用.方法 将高血压合并颈动脉粥样硬化患者60例随机分为两组.对照组给予西药常规治疗：均维持原标准治疗（根据临床需要选用利尿剂、钙拮抗剂、β-受体阻滞剂、血管紧张素转换酶抑制剂和血管紧张素受体阻滞剂）;治疗组在两组血压均有效控制在≤140/90 mmHg基础上,患者加服银杏叶提取物（天保宁）.两组疗程终点3m,3m后比较疗效和动脉硬化各项指标.结果 治疗组LDL、TC水平低于对照组,HDL水平高于对照组,斑块积分、动脉硬化指数及中医证侯积分治疗组小于对照组,LDL、斑块积分,中医证侯积分差异有统计学意义（P＜0.05）.结论 天保宁干预高血压动脉粥样硬化的有较好疗效.Objective To investigate the curative effect of taponing on hypertension-induced atherosclerosis through the assessment and comparison of the levels of TC, HDL, LDL and other clinical indicators, as well as the evaluation of plaque score, arterial stiffness index and TCM syndrome integral. Methods 60 cases of hypertensive patients with carotid atherosclerosis were randomly divided into-two groups： control group and observation group, 30 cases each group. The control group was treated with western medicine treatment, such as the use of diuretics, calcium antagonists, beta blockers, angiotensin converting enzyme inhibitors and angiotensin receptor blockers, etc. And the observation group was treated with EGb （taponing） plus the above treatment as the control group when the blood pressure effectively controlled within 140/90 mmHg in both two groups. The comparison of curative effect and arteriosclerosis indexes were analyzed after treatment for 3 months. Results In the observation group, the levels of LDL and TC, and plaque score, arterial stiffness index and TCM syndrome integral were lower, but HDL was higher than those of the control group. There were statistical differences in LDL, plaque score and TCM syndrome integral between the two groups （P〈0.05）. Coudusion Taponing has better curative effect on hypertension-induced atherosclerosis.

关 键 词：天保宁 动脉粥样硬化 高血压 

分 类 号：R544.1[医药卫生—心血管疾病]