提高微生物抗逆性技术的研究进展  

Reviews Related to the Techniques of Enhancing Microbial Stress Resistance

作　　者：刘玉萍[1] 唐鸿志[1] 许平[1] 

机构地区：[1]上海交通大学微生物代谢国家重点实验室,生命科学技术学院,上海200240

出　　处：《广州化工》2014年第24期4-6,共3页GuangZhou Chemical Industry

基　　金：国家自然基金(31422004);国家973计划(2013CB733901)

摘　　要：微生物体内存在多种抗逆基因或机制,这些机制的发现为定向提高微生物的抗逆性奠定了基础。提高微生物抗逆性的技术主要有过表达抗逆基因,长期适应性进化,genome shuffling(基因组改组)和异源表达抗逆基因等。利用这几种技术增强微生物的抗逆性,在以微生物为主的工业生产和环境污染物降解方面有着广阔的应用前景。Various stress resistant genes or mechanisms presented in microorganisms, and the discovery of these mechanisms laid a sound foundation for the directional enhancement of microbial stress tolerance. The main techniques of enhancing stress resistance of microorganisms contain over expression of stress-resistant genes, long-term adaptive evolution, genome shuffling, and heterologous expression of stress-resistant genes. These biological techniques can efficiently improve the stress resistance of industrial and environmental microorganisms, which surely benefited the bacteria based on industrial production and degradation of environmental pollutants.

关 键 词：微生物 抗逆性 工业生产 污染物降解 

分 类 号：Q939.99[生物学—微生物学]