气囊辅助小肠镜对Peutz-Jeghers综合征患者小肠息肉治疗的安全性评价  

Safety of balloon assisted enteroscopy for treatment of small bowel polyps in patients with Peutz-Jeghers syndrome

作　　者：俎站飞 毛高平[2] 张亚飞[2] 宁守斌[2] 

机构地区：[1]河北北方学院研究生院,河北省张家口市075000 [2]中国人民解放军空军总医院消化内科,北京市100142

出　　处：《世界华人消化杂志》2014年第33期5174-5178,共5页World Chinese Journal of Digestology

摘　　要：目的:客观评价气囊辅助小肠镜(balloon assisted enteroscopy,BAE)镜下切除PeutzJeghers综合征(Peutz-Jeghers syndrome,PJS)患者小肠息肉临床应用的安全性.方法:回顾性总结中国人民解放军空军总医院2004-04/2014-07应用BAE对181例PJS患者小肠息肉的内镜治疗情况,重点客观分析相关的并发症发生情况.结果:181例PJS患者(男101例,女80例)共进行了483例次BAE检查及治疗(经口285次,经肛198次),行BAE圈套切除小肠息肉共2680枚,B A E息肉切除术后一过性的轻微腹痛及/或腹部不适的发生率83.2%(397/483),穿孔的发生率1.4%(7/483),术中出血发生率10.1%(49/483),术后出血发生率1.9%(9/483),术后并发急性胰腺炎1例,无内镜治疗相关的死亡病例.结论:BAE治疗PJS患者小肠息肉尽管有一定风险和技术难度,但总体上并发症发生率较低,值得临床推广应用.AIM： To evaluate the safety of polypectomy by balloon assisted enteroscopy（BAE） in patients with Peutz-Jeghers syndrome（PJS）. METHODS： The clinical data for 181 patients with PJS treated at our hospital from April 2004 to July 2014 were analyzed retrospectively, and the related complications of polypectomy by BAE were analyzed.RESULTS： A total of 483 BAE procedures（285 peroral and 198 peranal） were carried out in 181 PJS patients（101 males and 80 females）, and a total of 2680 small intestinal polyps wereremoved by BAE. The incidence of transient mild abdominal pain and/or abdominal discomfort was 83.2%（397/483）. The incidences of perforation, intraoperative hemorrhage and postoperative hemorrhage were 1.4%（7/483）, 10.1%（49/483） and 1.9%（9/483）, respectively. Acute pancreatitis after operation occurred in one case, and there was no endoscopy related mortality. CONCLUSION： The overall incidence of complications of polypectomy by BAE in PJS patients is low.

关 键 词：PEUTZ-JEGHERS综合征 气囊辅助小肠镜 小肠息肉 安全性 

分 类 号：R574[医药卫生—消化系统]