青年男性急性高原反应与地理因素的关系研究  

Research on relationship between acute mountain sickness and geographic factors in young male

作　　者：宋桐林[1] 吴玉[1] 沈鹏宇[2] 刘运胜[1] 陈建[1] 田怀军[1] 

机构地区：[1]第三军医大学高原军事医学系,高原医学教育部重点实验室,高原医学全军重点实验室,重庆400038 [2]重庆医科大学公共卫生与管理学院,重庆400016

出　　处：《局解手术学杂志》2014年第6期599-602,共4页Journal of Regional Anatomy and Operative Surgery

基　　金：国家自然科学基金资助项目(41201090);卫生行业科研专项项目(201002012);国家科技支撑计划课题(2009BA185B01)

摘　　要：目的探讨地理因素与青年男性急性高原反应的关系,为高原易感人群的筛选及新的研究思路和方法提供参考。方法整群随机抽取同一批次从低海拔进入高海拔地区的294名青年男性,以问卷形式进行急性高原反应(AMS)发病情况调查,以军标进行AMS诊断。采用二元logistic回归方法,分析10种自然地理因素与AMS发病情况的关系,寻找引起不同地区人群AMS医学地理差异的危险因素。结果 AMS发病率为52.04%(153人),其中头晕、头痛、气短、胸闷、口唇发紫最常见,其发病率分别为89.54%、84.31%、66.01%、65.36%、60.78%。二元logistic回归分析发现,仅有海拔(OR=0.998,P<0.05)进入了回归模型。结论进入高原的人群中,其籍贯所在地海拔越低,越容易发生急性高原反应。对低海拔地区进入高原地区的人员,应采取针对性的预防措施确保其健康与安全。Abstact：Objective To study the relationship between acute mountain sickness and geographic factors in young males,and provide no-vel materials for screening susceptible population and exploring novel research ideas and methods. Methods Total 294 young men came from low altitude were randomly selected,questionnaire was conducted and military AMS standard was applied for diagnosis. Binary logistic re-gression was used to analyze the relationship between 10 different geographical factors and AMS incidence and figure out the risk factors for medical geographical differences of AMS. Results AMS incidence was 52. 04% （153 people）,with most commonly seen dizziness,head-ache,shortness of breath,chest tightness and lip empurples,the occurrence was 89. 54%,84. 31%,66. 01%,65. 36% and 60. 78%,respec-tively. Binary logistic regression analysis revealed that altitude was the only geographical risk factor （OR=0. 998,P〈0. 05）. Conclusion Among the population who entered plateau,lower native altitude they used to live brings higher risk of AMS,therefore corresponding preven-tions should be adapted for those who come to high altitude from low altitude in order to ensure their health and safety.

关 键 词：急性高原反应 地理因素 LOGISTIC回归分析 

分 类 号：R852.11[医药卫生—航空、航天与航海医学]