静电纺丝法制备PLLA/g-HNTs复合纳米纤维膜及其性能研究  

Preparation of PLLA / g-HNTs Composite Nanofiber Membranes by Electrospinning and Studies on Their Properties

作　　者：李慧华[1] 罗丙红[1] 秦小鹏[1] 李建华[1] 周长忍[1] 

机构地区：[1]暨南大学理工学院材料科学与工程系人工器官与材料教育部工程中心,广州510630

出　　处：《高分子学报》2015年第1期31-40,共10页Acta Polymerica Sinica

基　　金：国家自然科学基金(基金号81171459);暨南大学重点重大项目培育项目(项目号11611439)资助

摘　　要：以辛酸亚锡为催化剂,利用HNTs表面的羟基引发L-LA开环聚合,合成了表面接枝聚(L-乳酸)(PLLA)链段的埃洛石纳米管(g-HNTs),通过红外、热失重和透射电镜对改性前后HNTs的组成与形貌进行了观察;然后采用静电纺丝技术制备了PLLA纳米纤维膜以及不同组成的PLLA/HNTs和PLLA/g-HNTs复合纳米纤维膜,探讨了纺丝条件对纳米纤维膜形貌的影响,并对复合膜的组成、形貌、力学性能和细胞相容性进行了研究.结果表明,当HNTs与L-LA的摩尔投料比为1∶10时,g-HNTs表面PLLA链段的接枝率为14.22%,HNTs纳米管的形态在接枝后变化不大,易于在无水乙醇中分散.电压强度和进样速率对纤维膜的形貌有一定影响,当电压强度为15 k V、进样速率为1 m L/h时,电纺纤维的直径较为均匀.复合纤维膜中g-HNTs在基体PLLA中的分散性以及与基体的界面相容性要优于相应的HNTs,当g-HNTs含量高达40%时,复合纳米纤维膜中的纤维形态仍然保持较好,可以得到连续、粗细较均匀的纤维;随着HNTs和g-HNTs含量增加,复合纳米纤维膜的拉伸强度和模量先增大后下降,当HNTs和g-HNTs的含量为5%时,两种复合纳米纤维膜的拉伸强度和模量均达到最大值,但PLLA/g-HNTs组复合纳米纤维膜的拉伸强度始终大于相应的PLLA/HNTs组.体外3T3细胞培养结果显示,PLLA/g-HNTs复合纳米纤维膜具有良好的细胞相容性,且优于相应的PLLA和PLLA/HNTs纳米纤维膜.Through the ring-opening polymerization of L-lactide initiated by hydroxyl groups on the surface of HNTs using stannous 2-ethylhexanoate as catalyst, halloysite nanotubes surface-grafted with poly （L-lactic acid） （PLLA） segments （g-HNTs） were synthesized. The compositions and morphologies of the modified and unmodified HNTs were observed by Fourier transformation infrared （FTIR）, thermal gravimetric analysis （TGA） and transmission electron microscopy （TEM）. Then, a series of PLLA, PLLA/HNTs and PLLA/g- HNTs nanofiber membranes were prepared by electrospinning,the influences of the spinning conditions on the morphologies of the nanofiber membranes were discussed, and the composition, micrograph, interfacial compatibility,tensile properties and cellular compatibility of the composite membranes were studied too. Results showed that the grafting percentage of PLLA segments on the surface of g-HNTs was 14.22% as the molar ratio of HNTs to L-lactide was 1： 10. The tubular morphology of HNTs changed little after surface grafting,and g-HNTs can easily disperse in anhydrous ethanol. The voltage and the feed rate have effects on the morphology of fiber membranes,when the voltage was 15 kV and feed rate was 1 mL/h,the diameter of the electrospinning fiber was relatively uniform. The dispersion and interfacial compatibility of g-HNTs in PLLA matrix were superior to those of pristine HNTs,when the content of g-HNTs increased up to 40 wt% , the fiber micrograph of the PLLA/g-HNTs composite membranes continues to remain good, and continuous and relatively uniform fiber can be got. With the content of HNTs and g-HNTs increased,the tensile strength and modulus increased first and then decreased,as the filler content was 5 wt% ,the highest tensile strengths and moduli were obtained for both of the PLLA/HNTs and PLLA/g-HNTs composite nanofiber membranes. However,the tensile strength and modulus of the PLLA/g-HNTs composite nanofiber membranes were always higher than those of PLLA/ HNTs composite nanofiber

关 键 词：聚乳酸 埃洛石 表面接枝 静电纺丝 性能 

分 类 号：TQ340.64[化学工程—化纤工业]