我院心血管介入手术抗菌药物使用与影响因素的调查分析  

Investigation and Analysis of Antibiotics Use and Its Influential Factors of Cardiovascular Interventional Operation in Our Hospital

作　　者：李春雷[1] 李聪[1] 刘慧敏[1] 朱雪松[1] 李鹏[1] 何培根[2] 

机构地区：[1]湖北医药学院附属东风医院药学部,湖北十堰442008 [2]湖北医药学院附属东风医院心内科,湖北十堰442008

出　　处：《中国药房》2015年第2期182-184,共3页China Pharmacy

摘　　要：目的:为心血管介入手术规范、合理使用抗菌药物提供参考。方法:采用回顾性队列研究,设计相同的调查表,统计分析心血管介入手术患者的抗菌药物使用与影响因素之间的联系。搜集我院2011年7-9月心血管介入手术病例310例作为对照组,2012年7-9月心血管介入手术病例318例作为干预组,对两组预防使用抗菌药物合理情况进行比较分析。结果:通过干预,我院心血管介入手术预防使用抗菌药物应用率由79.3%降至干预后的32.7%,抗菌药物预防使用趋于合理,围术期护理情况、手术部位、手术类型和并发疾病是影响心血管介入手术使用抗菌药物的主要因素。结论:我院心血管介入手术抗菌药物使用合理性大大增加,加强院感控制和患者围术期护理有利于降低心血管介入手术抗菌药物的使用率,提高使用的合理性。OBJECTIVE ： To provide reference for rational use of antibiotics in cardiac interventional surgery. METHODS ： By using retrospective cohort study, designing same questionnaires, the correlation of antibiotics use with influential factors in patients underwent cardiac interventional surgery were analyzed statistically. 310 cases of our hospital from Jut. to Sept. in 20 t t were includ- ed in control group, and 318 cases of cardiac interventional surgery from Jul. to Sept. in 2012 in intervention group. Rationality of prophylactic application of antibiotics was analyzed comparatively in 2 groups.RESULTS： After antibiotics intervention, utilization ratio of prophylactic use of antibiotics in cardiac interventional surgery decreased from 79.3% in 2011 to 32.7% in 2012. The pro- phylactic use of antibiotics became more rational. Perioperative nursing care, operation site, operation type and complicating with diseases were major factors that affected the use of antibiotics. CONCLUSIONS： The rationality of antibiotics use in our hospital has been improved greatly, but it is necessary to strengthen nosocomial infection control and perioperative nursing care so as to re- duce the use of antibiotics in cardiac interventional surgery and improve rationality of drug use.

关 键 词：心血管 介入手术 抗菌药物 影响因素 

分 类 号：R969.3[医药卫生—药理学] R978.1[医药卫生—药学]