热毒宁联合蒙脱石散治疗婴幼儿病毒性肠炎  

Reduning combined with montmorillonite powder for infantile viral enteritis

作　　者：曹永宁 王永莉 

机构地区：[1]陕西铜川市矿务局中心医院麻醉科,727000

出　　处：《国际中医中药杂志》2015年第1期44-46,共3页International Journal of Traditional Chinese Medicine

摘　　要：目的：观察热毒宁联合蒙脱石散治疗婴幼儿病毒性肠炎的临床疗效。方法选取2010年8月－2013年10月陕西铜川市矿务局中心医院儿科住院病毒性肠炎患儿136例，采用随机数字表法分为2组，热毒宁组（65例）选用热毒宁注射液治疗，联合治疗组（71例）在热毒宁组治疗基础上加服蒙脱石散。比较2组患儿的治疗总有效率、症状改善时间及住院时间。结果联合治疗组总有效率（69/71，97.2%）显著高于热毒宁组（39/65，60.0%）（χ2＝26.467，P＜0.05）。联合治疗组退热时间[（2.96±1.32）d比（3.84±1.94）d；t＝2.587，P＝0.011]、止泻时间[（3.12±1.44）d比（3.95±1.97） d；t＝2.340，P＝0.022]及住院时间[（4.60±1.62）d比（5.86±2.35）d；t＝3.044，P＝0.003]均较热毒宁组显著缩短。结论热毒宁联合蒙脱石散治疗婴幼儿病毒性肠炎可缩短病程和住院时间，疗效优于单用热毒宁。Objective To observe the therapeutic effects of Reduning combined with montmorillonite powder for infantile viral enteritis. Methods A total of 136 patients with infantile viral enteritis in Shanxi Tongchuan Mining Bureau Central Hospital pediatric clinic from August 2010 to October 2013 were selected and divided into two group by random number table method, a Reduning group （65 cases） and a combined treatment group （71 cases）. The Reduning group was treated with Reduning injection and the combined treatment group was treated with Reduning injection plus oral montmorillonite powder. The total efficiency, improvement of symptoms and staying hospital time were compared between the two groups. Results The total effective rate in the combined treatment group was significantly higher than that in the Reduning group （97.1% vs. 59.9%, χ2=28.696, P〈0.05）. The fever clearance time （2.96 ± 1.32 d vs. 3.84 ± 1.94 d; t=2.587, P=0.011）, the time to stop diarrhea （3.12 ± 1.44 d vs. 3.95 ± 1.97 d;t=2.340, P=0.022） and staying hospital time （4.60 ± 1.62 d vs. 5.86 ± 2.35 d;t=3.044, P=0.003） in the combined treatment group were all shorter than those in the Reduning group. Conclusions Reduning combined with montmorillonite powder is more effective in the treatment of infantile viral enteritis than Reduning alone, which shortens the course and staying hospital time.

关 键 词：肠炎 轮状病毒感染 热毒宁 蒙脱石散 

分 类 号：R725.1[医药卫生—儿科]