苯乙酮基吡啶季铵盐与醇的反应  

Reactions of Acetophenonyl Pyridinium Salts with Alcohols

作　　者：佘川[1] 周洁[1] 陈慧[1] 刘绪峰[1] 张万轩[1] 

机构地区：[1]湖北大学有机化工新材料湖北省协同创新中心有机功能分子合成与应用教育部重点实验室,武汉430062

出　　处：《有机化学》2014年第12期2551-2553,共3页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金(No.20872031);有机功能分子合成与应用教育部重点实验室资助项目~~

摘　　要：苯乙酮基吡啶季铵盐具有多种反应活性，但它带有的羰基的反应性很少引起人们的关注。研究发现苯乙酮基吡啶季铵盐在碱性条件下与醇（或酚）反应时，吡啶基带着α-碳原子离去，生成相应的苯甲酸酯类物质。与醇反应时产率较高（80%～98%），与苯酚反应时，产率为48%。Acetophenonyl pyridinium salts are versatile reagents in organic reactions, but the reactivities of their carbonyls were seldomly studied. It was found that the reactions of the carbonyls with alcohols occurred when acetophenonyl pyridinium salts were treated with alcohols （or phenol） in the presence of a base giving rise to benzoates, and the departure of pyridyl with theα-carbon atom was involved. High yields （80%~98%） were achieved when they reacted with alcohols, however a yield of 48%were obtained when phenol was used instead of alcohols.

关 键 词：苯乙酮基吡啶季铵盐 醇 苯甲酸酯衍生物 

分 类 号：O625.523[理学—有机化学]