慢性阻塞性肺疾病急性加重期合并血小板减少60例的诊治体会  

Diagnosis and treatment experience of 60 cases of AECOPD thrombocytopenia

作　　者：吴明亚[1] 李光清[1] 吴昭萍[1] 李小波[1] 亓占中[1] 陈秋伶[1] 王馨平[1] 张琼[1] 白光洪[1] 梁颖隽[1] 袁娇[1] 李东[1] 

机构地区：[1]解放军第452医院呼吸内科,四川成都610021

出　　处：《四川医学》2014年第12期1573-1575,共3页Sichuan Medical Journal

摘　　要：目的探讨慢性阻塞性肺疾病急性加重期(AECOPD)合并血小板减少的原因及临床处理方法。方法回顾分析我科2010年至2014年间60例AECOPD患者合并血小板减少患者临床资料。结果 50%无需特殊升血小板治疗,30%给予糖皮质激素及预防出血处理,15%加用重组人白介素II(巨和粒)升血小板,5%需要进一步输注新鲜血小板治疗。对于出现局部皮下出血的患者及时停用可能导致血小板减少的一切药物。结论虽然AECOPD患者住院治疗期间导致血小板减少的原因、机制不明确,从本组病例的分析得出与药源性、感染性有一定相关性。Objective To discuss the reason and clinical treatment of thrombocytopenia of AECOPD. Methods Ana-lyzed the clinical data of 60 cases of AECOPD thrombocytopenic patients from 2010 to 2014. Results 50% without special in-creasing platelets treatment,30% with glucocorticoid and preventhemorrhage treatment,15% with increase platelets treatment by Recombinant Human Interleukin-II（juheli）,5% with further fresh platelet transfusion treatment. Drugs may cause thrombocytope-niahave to be stopped immediately on local subcutaneoushemorrhage patients. Conclusion Although the reasons of induced throm-bocytopenia of AECOPD patients duringhospitalization are not clear,we can still find certain drug-induced and etiologic relativity from the analysis of the cases.

关 键 词：慢性阻塞性肺病 血小板减少 诊治体会 

分 类 号：R563.9[医药卫生—呼吸系统] R558.2[医药卫生—内科学]