良性前列腺增生常见中医证型分布规律及相关因素研究  

The Chinese medicine syndrome distribution characteristics and relevant factors study of benign prostatic hyperplasia

作　　者：韩旭[1] 孙淑艳[1] 

机构地区：[1]北京中医药大学第三附属医院,北京100029

出　　处：《现代中医临床》2014年第6期16-18,共3页Modern Chinese Clinical Medicine

基　　金：北京中医药大学自主选题项目中青年教师资助项目类(No.3030207030412)

摘　　要：目的探讨良性前列腺增生中医证型分布规律以及其与年龄、国际前列腺症状评分表(IPSS)评分、血清前列腺特异性抗原(TPSA)的相关性。方法对北京、深圳地区几家医院就诊的前列腺增生患者中医证型和相关指标进行大样本(1 052例)临床调查,制定前列腺增生临床调查表,建立数据库,选用合适的统计方法进行分析。结果出现频率最多的证型是肾气亏虚型和湿热下注型,最少的是肝郁气滞型。不同年龄证型分布有一定差异。TPSA与肝郁气滞的关系有统计学意义(P=0.020),TPSA阳性患者属于肝郁气滞证的概率高于阴性患者(OR=3.431)。IPSS评分与各证型无相关性。结论良性前列腺增生中医证型分布有一定规律,且与年龄、TPSA有相关性。Objective To discuss the traditional Chinese medicine （TCM） syndrome distribution characteristics of benign prostatic hyperplasia and its relationship with age, international prostate symptom score （IPSS） and total prostate specific antigen （TPSA）. Methods 1052 cases of prostatic hyperplasia patients from hospitals of Beijing and Shenzhen were collected, including TCM syndrome and relative indicators. Moreover, the clinical questionnaire was built up, and a database was established. The adequate statistical methods had been conducted for analysis. Results The top 2 most frequency syndrome were kidney qi deficiency and danmpness-heat diffusing downward. The least frequency syndrome was liver qi stagnation. Different distribution characteristics of TCM syndrome showed in different ages. Significant differences showed in the relationship between TPSA and liver qi stagnation（P= 0.020）, and the probability of carrying liver qi stagnation by patients with TPSA positive was higher than patients with TPSA negative （OR=3.431）. There was no correlation between IPSS and syndromes. Conclusion There is a regular pattern of TCM syndrome distribution in benign prostatic hyperplasia, and it is related with age and TPSA.

关 键 词：前列腺增生 证候 分布特点 前列腺特异性抗原 

分 类 号：R256.53[医药卫生—中医内科学]