陈皮、白术挥发油的提取及其包合工艺的研究  

On Extraction and Inclusion Processes of Essential Oil in Atractylodis Macrocephalae Koidiz. and Citri Reticulatae Pericarpium

作　　者：田金凤[1] 尚远宏[1,2] 王深红 汪宏锦 杨艳涵 刘圆[3] 

机构地区：[1]攀枝花学院医学院干热河谷特色生物资源研发四川省高校重点实验室,四川攀枝花617000 [2]西南大学药学院重庆市药效评价工程技术研究中心,重庆400716 [3]西南民族大学民族医药研究院,成都610041

出　　处：《西南师范大学学报（自然科学版）》2014年第12期65-68,共4页Journal of Southwest China Normal University(Natural Science Edition)

基　　金：国家自然科学基金资助项目(81173653);国家科技支撑计划项目(2012BAI27B07);四川省高校重点实验室开放基金项目(GR-2013-E-02);四川省教育厅重点基金项目(14ZA0345);攀枝花市社会发展科技计划项目(2014TX-10-3)

摘　　要：确定陈皮、白术挥发油提取及其包合物制备最佳工艺.方法:水蒸气蒸馏提取挥发油和饱和水溶液法制备包合物,并用正交试验法,对挥发油提取与β-环糊精的包合进行3因素3水平考察.结果:最佳提取工艺A2B2C3,即陈皮、白术粉碎成过50目筛的粉末,加10倍水量,提取5h;最佳包合工艺A3B2C1,即用挥发油与β-CD投料比为1∶6,50℃搅拌包合5h,包合率为81.90%.结论:提取和包合工艺简单、易行、成本较低.The paper is related to the investigation of the optimum extraction and inclusion condition of es‐sential oil in A tractylodis macrocephalae Koidiz .and Citri reticulatae pericarpium .The technique of ex‐traction and inclusion are steam distillation method and saturated water solution ,respectively .3 factors and 3 levels orthogonal design have been adopted to explore the optimum conditions .Extreme difference a‐nalysis and variance analysis has been used for data processing .Conditions for the extraction and inclusion of essential oil have been studied .Best extraction process of essential oil in A tractylodis macrocephalae Koidiz .and Citri reticulatae pericarpium is A2 B2 C3 ：raw drug materials are boiled 5 hours by addition of 10 times of water to the middle powder （50 mesh screen） of A tractylodis macrocephalae Koidiz .and Citri reticulatae pericarpium .Moreover ,its best inclusion process is A3B2C1 ：the proportion of essential oil andβ‐cyclodextrin is 1 ：6 ,inclusion time is 1h at the temperature of 50 ℃ ,inclusion rate is 81 .90 % .It is concluded that the extraction and inclusion process of essential oil from A tractylodis macrocephalae Koidiz .and Citri reticulatae pericarpium are simple ,available and economic .

关 键 词：β 环糊精 挥发油 水蒸气蒸馏法 陈皮 白术 

分 类 号：TQ461[化学工程—制药化工]