早期目标导向治疗糖尿病合并脓毒性休克48例临床观察  

Clinical observation on 48 cases of early goal- directed therapy in diabetic patients with septic shock

作　　者：高宇[1] 张军建[1] 邹世斌[1] 

机构地区：[1]四川省自贡市第三人民医院ICU,四川自贡643000

出　　处：《吉林医学》2015年第1期17-19,共3页Jilin Medical Journal

摘　　要：目的:观察早期目标导向治疗(EGDT)糖尿病合并脓毒性休克患者的临床效果。方法:将48例糖尿病合并脓毒性休克患者随机分为治疗组(n=24)和对照组(n=24),治疗组采用EGDT,对照组采用常规复苏治疗。观察两组治疗后血流动力学指标、氧代谢指标、血糖控制、MODS发生率、28 d病死率。结果:两组患者入选时的病情差异无统计学意义(P>0.05),治疗组治疗后6 h及24 h的血流动力学指标、氧代谢指标、血糖控制水平、MODS发生率、28 d病死率与对照组比较差异有统计学意义(P<0.05)。结论:EGDT能显著改善糖尿病合并脓毒性休克患者预后。Objective To observe the early ＂goal- directed therapy＂ （EGDT） on diabetic clinical effect of septic shock. Method 48 cases of diabetic patients with septic shock were randomly divided into treatment group （ n = 24） and the control group （ n = 24）, the treatment group was given the early goal -directed therapy, the control group was given conventional recovery treatment. To observe the hemodynamic indexes of the two groups after treatment, the metabolism of oxygen index, blood sugar control 28 days, MODS incidence, mortality. Results Two groups of patients was no statistical difference （P 〉 0. 05 ）, the treatment group after treatment 6 h and 24 h, hemodynamic index, oxygen metabolism index, blood sugar control level 28 days, MODS incidence, mortality compared with the control group were statistically difference （ P 〈 0.05 ）. Conclusion Early goal - directed therapy can significantly improve the prognosis of patients with diabetes complicating septic shock.

关 键 词：脓毒性休克 早期目标导向治疗 糖尿病 病死率 

分 类 号：R459.7[医药卫生—急诊医学] R587.1[医药卫生—治疗学]