儿童肺炎克雷白杆菌感染的危险因素及耐药性变迁  

Risk factors of klebsiella pneumoniae infection and drug resistance

作　　者：程超[1] 李玖军[1] 

机构地区：[1]中国医科大学附属盛京医院PICU,沈阳110004

出　　处：《中国小儿急救医学》2015年第1期52-55,共4页Chinese Pediatric Emergency Medicine

摘　　要：肺炎克雷白杆菌属于肠杆菌科克雷白菌属,也是重要的条件致病菌与医院内感染的病原菌,可以引起严重或致死性感染.肺炎克雷白杆菌院内感染比例逐年增加,其对多种抗生素耐药,并且其耐药性不断变迁.临床耐药株包括耐碳青霉烯类肺炎克雷白杆菌、多重耐药肺炎克雷白杆菌、广泛耐药肺炎克雷白杆菌和全耐药肺炎克雷白杆菌.肺炎克雷白杆菌的医院感染危险因素主要为基础疾病严重程度及住院时间、机械通气、抗生素使用种类和数量等.Klebsiella Pneumoniae is a opportunity infection and nosocomial infection bacteria in Enterobacteriaceae,which can lead to serious infection or death.Klebsiella Pneumoniae leads to increased infections proportion in recent years,which resisits to many common antibiotics.Clinical drug resistant strains include Carbapenem-resistant Klebsiella Pneumoniae,Multidrug-resistant Klebsiella Pneumoniae,Extensively drug resistant bacteria and Pandrug-resistant Klebsiella Pneumoniae.Researches beared out that the risk factors of acquiring nosocomial infection of Klebsiella Pneumoniae are state of an illness,time of hospitalization,mechanical ventilation,the kind and number of antibiotics.

关 键 词：肺炎克雷白杆菌 感染 耐药性变迁 

分 类 号：R446.5[医药卫生—诊断学]