头痛新1号治疗慢性偏头痛的临床研究  

Clinical Study of ToutongXinNO.1 in Treating Patients with Chronic Migraine Headaches

作　　者：姜婷婷[1] 李慧[2] 白方会[1] 伍志勇[1] 聂玲辉[1] 陈宝田[1] 

机构地区：[1]南方医科大学南方医院中医科,广东广州510515 [2]广州市红十字会医院中医科,广东广州510515

出　　处：《云南中医学院学报》2014年第6期36-38,55,共4页Journal of Yunnan University of Traditional Chinese Medicine

基　　金：国家自然科学基金(81202687);广东省科技计划项目(2012B061700018)

摘　　要：目的探讨头痛新1号治疗慢性偏头痛的临床疗效。方法将80例慢性偏头痛患者随机分为治疗组和对照组,采用焦虑自评量表(SAS)及抑郁自评量表(SDS)评价其焦虑和抑郁程度。治疗组予头痛新1号,对照组予盐酸氟桂利嗪,2组疗程均为12周,治疗后比较各组间差异。结果 2组治疗前后头痛程度、发作频率及持续时间比较均有显著差异(P<0.001);治疗组、对照组临床总有效率分别为95%,70%,组间比较有差异(P<0.05);服药12周后治疗组SDS和SAS评分明显降低(P<0.001),对照组差异不明显(P>0.001)。结论头痛新1号治疗慢性偏头痛疗效显著,能有效改善头痛患者伴随的情绪障碍。因此,慢性偏头痛应从风、从湿、从瘀、从虚、从郁综合治疗。Objective To explore the clinical curative effect of Toutong Xin NO. 1（TX1） in treating patients with chronic migraine headaches. Methods 80 cases of chronic migraine（CM） patients were randomly divided into two groups,evaluating the degree of anxiety and depression of patients with CM by Self-rating Anxiety Scale（SAS）and Self-rating Depression Scale（SDS）,the treatment group who received TX1;and the control group who received Flunarizine Hydrochloride Capsules. The treatment lasted for12 weeks. To observe the difference in two groups. Results There were significantly differences between two groups（P〈0.001） in degree,frequency,and duration,before and after the therapy. The effective rates of clinical effect were 95% and 70% in treatment group and control group respectively,the difference was statistically significant（P〈0.05）. After the therapy,the treatment group had the marked decrease in SAS and SDS（P〈0.001）,and no marked difference in the control group（P〉0.001）. Conclusion TX1 is Significantly effective in treating CM,and reducing the depression. CM should be treated based on wind,dampness,blood stasis,deficiency,and the depression.

关 键 词：头痛新1号 慢性偏头痛 盐酸氟桂利嗪 

分 类 号：R255[医药卫生—中医内科学]