三维斑点追踪成像技术评价舒张功能减低时左室心肌收缩功能  

THREE-DIMENSIONAL SPECKLE TRACKING IMAGING ASSESSMENT OF LEFT VENTRICLE SYSTOLIC PERFORMANCE IN PATIENTS WITH LEFT VENTRICULAR DIASTOLIC

作　　者：邓晓丽[1] 吴棘[1] 李蔚[1] 陈超容[1] 林海红[1] 刘雪玲[2] 

机构地区：[1]广西医科大学第一附属医院超声科,南宁530021 [2]广西中医药大学第一附属医院超声科

出　　处：《广西医科大学学报》2014年第6期932-934,共3页Journal of Guangxi Medical University

基　　金：广西科学研究与技术开发计划项目(No.1298003-3-1);广西自然科学基金资助项目(No.2013GXNSFAA019173)

摘　　要：目的:运用三维斑点追踪成像技术分析左室舒张功能减低患者左室心肌整体收缩期应变能力及其收缩功能的变化,探讨该技术在评价左室收缩功能的临床价值。方法:根据左室舒张功能状态将69例左室舒张功能减低患者分成3组,即松弛功能减退组28例、伪正常化组21例和限制型充盈组20例;正常组30例。采用三维斑点追踪成像技术分别获取各组左室整体心肌收缩期纵向应变峰值(GPSL)、圆周应变峰值(GPSC)、径向应变峰值(GPSR)、面积应变峰值(GPSA)、左室射血分数(LVEF)、左室舒张末期容积(LVEDV)及左室收缩末期容积(LVESV),比较4组间各超声指标的差异。结果:伪正常化组与限制型充盈组间GPSL,GPSR,GPSC相比差异有统计学意义(P<0.05),伪正常化组大于正常组,限制型充盈组小于正常组(P<0.05);GPSA在松弛功能减退组及伪正常化组大于正常组,在限制型充盈组明显小于正常组(P<0.05);限制型充盈组中各指标值均小于其它各组(P<0.05)。结论:三维斑点追踪成像技术可客观、全面的评价左室舒张功能减退患者左室心肌整体收缩期应变能力。面积应变能更早发现左室心肌的形变受损情况,为临床评价左室收缩功能提供更可靠的依据。Objective：To analysis left ventricular global systolic strain capacity in patients with diastolic dysfunction using three-dimensional speckle tracking imaging,and to study the change of systolic performance when the left ventricular diastolic dysfunction,then to explore the clinical value of the technology in assessing systolic performance for the patients with left ventricular diastolic dysfunction.Methods：According to the state of the left ventricular diastolic performance,69 patients with left ventricular diastolic dysfunction were divided into three groups namely：relaxation dysfunction group,pseudo-normalization group and restrictive filling group.The control group was selected from 30 normal subjects.For each case the left ventricular end-systolic global peak longitudinal strain （GPSL）,global peak eircumferentail strain （GPSC）,global peak radial strain （GPSR）,global peak area strain （GPSA）,left ventricular ejection fraction （LVEF）,end-diastolic volume（EDV） and end-systolic volume（ESV） were obtained by the three-dimensional speckle tracking imaging.Then the indicators were analyzed and compared among the four groups.Results：The GPSL,GPSC and GPSR were statistically different among the pseudo-normalization group and the restrictive filling group （P ＜0.05）,the pseudo-normalization group was higher while the restrictive filling group was lower than the normal group.GPSA was statistically significant among the four groups （P ＜0.05）,the relaxation dysfunction group and the pseudo-normalization group was higher than the normal group while the restrictive filling group was significantly lower than the normal group.The values of the left ventricular end-systolic global peak strain were the smallest for the restrictive filling obstacle group in the four groups （P ＜ 0.05）.Conclusion：Three-dimensional speckle tracking imaging can be objective and comprehensive assess the left ventricular global systolic performance in patients with left ventricular diastolic dysfun

关 键 词：三维斑点追踪成像技术 舒张功能减低 收缩功能 应变 

分 类 号：R445.1[医药卫生—影像医学与核医学]