益气活血法预防糖尿病足腔内介入后再狭窄的观察  

Clinical Observation of Yiqihuoxue Therapy on Preventing Diabetic Endovascular Stent Restenosis Foot

作　　者：李强[1] 于宗学[2] 苗进[1] 

机构地区：[1]青岛大学医学院附属海慈医院,山东青岛154007 [2]青岛市第三人民医院,山东青岛154007

出　　处：《中医临床研究》2014年第36期61-63,共3页Clinical Journal Of Chinese Medicine

基　　金：青岛市卫生局资助项目2014-zyy009

摘　　要：目的:观察益气活血法预防糖尿病足腔内介入后再狭窄的临床疗效。方法:选择接受腔内治疗的糖尿病足患者370例,分为中药组与对照组,其中中药组185例,对照组185例。所有患者都给予抗血小板药物口服,中药组予益气活血法辨证加减口服中药。观察两组患者术后24个月间歇性跛行、静息痛、踝肱指数(ABI)、肢体再次溃疡或者坏疽及截肢等情况,并进行统计学分析。结果:24个月后,对照组中,1例患者膝下截肢,1例患者膝上截肢,1例患者出现左足趾溃疡,1例患者出现左足趾坏疽,中药组中仅出现1例左足趾坏疽。其中中药组再次出现间歇性跛行、静息痛症状均少于对照组(P<0.01),中药组ABI明显高于对照组(P<0.05)。结论:益气活血法可明显提高糖尿病足腔内治疗术后血管通畅率,改善肢体缺血症状。Objective：To observe the clinical effects of Yiqihuoxue therapy on preventing diabetic endovascular stent restenosis foot. Methods： 370 diabetic foot （DF） that successfully underwent endovascular therapy were randomly divided into two groups,the control group and the treatment group,185 in each group. Patients in the control group received antiplatelet treatment,while the treatment group was additionally Yiqihuoxue herbal medicine. Ankle brachial index （ABI）,intermittent claudication,rest pain,ulcer,gangrene and the incidence of amputation in the following 24 months were recorded and observed in the two groups. Statistical analysis and comparison of observation was carried out with SPSS17.0. Results： After 24 months, in the control group, 1 patient received an above the knee amputation, 1 patient received an below the knee amputation, 1 patient had ulcer in his left foot,1 patient had gangrene with his left foot. In the treatment group, only 1 patient had gangrene in his left foot without amputation. Compared to the control group,the incidence rate of intermittent claudicating and the rest pain significantly decreased （ P〈0.01）;ABI was significantly higher than that of the control group （ P〈0.05）.Conclusion：Yiqitongluo therapy can effectively improve ischemic symptoms of affected limbs through reducing the restenosis rate after endovascular therapy of Yiqitongluo herbal medicine.

关 键 词：糖尿病足 益气活血法 腔内治疗 再狭窄 

分 类 号：R473.5[医药卫生—护理学]