Radiotherapy reliability analysis based on PSA method  

作　　者：李文艺 曹瑞芬 裴曦 胡丽琴 

机构地区：[1]Key Laboratory of Neutronics and Radiation Safety, Institute of Nuclear Energy Safety Technology, Chinese Academy of Sciences [2]Engineering Technology Research Center of Accurate Radiotherapy of Anhui Province [3]Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions

出　　处：《Nuclear Science and Techniques》2014年第6期69-74,共6页核技术（英文）

基　　金：Supported by the National Natural Science Foundation of China(No.81101132);the Natural Science Foundation of Anhui Province(No.11040606Q55)

摘　　要：The reliability of radiotherapy was evaluated and effective approaches were obtained in order to improve radiotherapy quality by using the Probabilistic Safety Assessment(PSA) method. This study investigated the feasibility of the PSA method being applied to radiotherapy through Image-guided Radiotherapy(IGRT) and chest tumor irradiation. A fault tree has been constructed after analyzing causal relationship of the events.After calculating Risk A, a total inaccuracy radiotherapy probability and the importance of all base events were obtained. The probability of inaccurate radiotherapy was 2.87%. Under the condition that the target delineation was perfectly right, the accuracy of radiotherapy significantly improved. With the calculation without Conebeam Computed Tomography(CBCT) being corrected before irradiation, the accuracy significantly decreased.The most important events were connected with the human factor. Improving human technical level could enhance radiotherapy quality control efficiently.The reliability of radiotherapy was evaluated and effective approaches were obtained in order to improve radiotherapy quality by using the Probabilistic Safety Assessment（PSA） method. This study investigated the feasibility of the PSA method being applied to radiotherapy through Image-guided Radiotherapy（IGRT） and chest tumor irradiation. A fault tree has been constructed after analyzing causal relationship of the events.After calculating Risk A, a total inaccuracy radiotherapy probability and the importance of all base events were obtained. The probability of inaccurate radiotherapy was 2.87%. Under the condition that the target delineation was perfectly right, the accuracy of radiotherapy significantly improved. With the calculation without Conebeam Computed Tomography（CBCT） being corrected before irradiation, the accuracy significantly decreased.The most important events were connected with the human factor. Improving human technical level could enhance radiotherapy quality control efficiently.

关 键 词：可靠性分析 PSA 放疗 计算机断层扫描 放射治疗 误差概率 质量控制 故障树分析 

分 类 号：R730.55[医药卫生—肿瘤]