苯妥英钠对比丙戊酸钠治疗癫痫效果分析  

Contrast phenytoin sodium valproate treatment of epilepsy results analysis

作　　者：王真真[1] 李津军[1] 樊彬[1] 满高才 祁洪凯 

机构地区：[1]滨州医学院附属医院,山东滨州256600

出　　处：《临床医药文献电子杂志》2014年第15期1962-1963,共2页Electronic Journal of Clinical Medical Literature

摘　　要：目的：对比苯妥英钠与丙戊酸钠治疗癫痫的临床效果。方法收集2013年7月～2014年7月本院收治的60例癫痫患者临床效果，遵循随机原则，分为A组30例、B组30例。A组取丙戊酸钠治疗，B组取苯妥英钠治疗，对比患者疗效。结果两组患者治疗有效率、特异性反应发生率对比（P〉0.05）。A组患者剂量相关的不良反应发生率、慢性不良反应发生率低于B组（P〈0.05）。结论丙戊酸钠、苯妥英钠治疗癫痫，疗效相当，但丙戊酸钠不良反应发生率较低。Objective To contrast and phenytoin sodium valproate in the treatment of epilepsy. Methods Collecting July 2013 to July 2013 in our hospital were 60 cases of epilepsy patients clinical effect, adhere to the principle of random, 30 cases were divided into group A and B group 30 cases. Taking valproate treatment group A and group B taking phenytoin sodium treatment, compared to patients with therapeutic effect.Results Two groups of patients treatment efficient and specific reaction rate comparison （P 〉0.05）. Group A dose related incidence of adverse reactions, patients with chronic lower incidence of adverse reactions than group B （P〈0.05）. ConclusionValproic acid, sodium phenytoin sodium treatment of epilepsy, curative effect, but valproic acid sodium low incidence of adverse reactions.

关 键 词：丙戊酸钠 苯妥英钠 癫痫 

分 类 号：R971.6[医药卫生—药品]