Three-Dimentional Surface Light Irradiance Reconstruction in Bioluminescence Tomography  

作　　者：陈春晓 刘高 张倩 李婷婷 王正盛 黎宁 

机构地区：[1]College of Automation Engineering,Nanjing University of Aeronautics and Astronautics [2]College of Science,Nanjing University of Aeronautics and Astronautics [3]College of Electronic and Information Engineering,Nanjing University of Aeronautics and Astronautics

出　　处：《Transactions of Nanjing University of Aeronautics and Astronautics》2014年第6期652-659,共8页南京航空航天大学学报（英文版）

基　　金：Supported by the National Natural Science Foundation of China(61171059);the Fundamental Research Funds for the Central Universities of China(NP2012202,NZ2014101);the Foundation of Graduate Innovation Center in Nanjing University of Aeronautics and Astronautics(kfjj201427)

摘　　要：Reconstruction of 3D surface irradiance distribution using multiple views captured by charged coupled device(CCD)camera is the basis of solving the light source in bioluminescence tomography(BLT).A simple and convenient mapping technique based on the pin-hole imaging model and Lambert′s cosine law was presented to establish the relationship between gray levels and irradiance intensities.Compared with previous integrating sphere camera calibration used in BLT,the proposed method can effectively avoid heavy burden of simulation experiment to obtain the corresponding relationship of gray levels and irradiance intensities.The accuracy and feasibility of the proposed method are validated with no more than 1mm location error by different types of phantom experiments.The mapping approach is also applicable to other noncontact optical imaging system.Reconstruction of 3D surface irradiance distribution using multiple views captured by charged coupled device （CCD） camera is the basis of solving the light source in bioluminescence tomography （BLT）. A simple and convenient mapping technique based on the pin-hole imaging model and Lambert＇s cosine law was presented to es tablish the relationship between gray levels and irradiance intensities. Compared with previous integrating sphere camera calibration used in BLT, the proposed method can effectively avoid heavy burden of simulation experiment to obtain the corresponding relationship of gray levels and irradiance intensities. The accuracy and feasibility of the proposed method are validated with no more than 1 mm location error by different types of phantom experiments. The mapping approach is also applicable to other noncontact optical imaging system.

关 键 词：light propagation model irradiance reconstruction bioluminescence tomography(BLT) pin-hole imaging 

分 类 号：TN21[电子电信—物理电子学]