药物不良反应2012~2013年127例报告分析  

2012-2013, 127 cases of adverse drug reactions report analysis

作　　者：宋瑞雪[1] 

机构地区：[1]江苏省丰县人民医院药剂科,江苏徐州221700

出　　处：《临床医药文献电子杂志》2014年第18期2614-2615,共2页Electronic Journal of Clinical Medical Literature

摘　　要：目的 探讨我院药品不良反应（ADR）一般规律与发生因素和特征,从而为临床合理用药和安全用药提供依据。方法 收集2012~2013年127例药物不良反应报告进行分析,根据药品的给药途径、药品类型、ADR程度、ADR所涉及器官和系统、临床表现等做分析。结果 本次研究中共涉及127份药物,其中抗菌药物居首位,中成药紧随其后;因静脉滴注而引发的ADR121例,占95.3%;DAR可发生于人体内的每个系统和器官,可表现为变态反应,皮肤损害最为严重,其次为神经系统受损。结论 应该针对DAR情况加强监测力度,并将ADR的相关知识进行宣传普及,指导临床进行合理用药,尽量将DAR发生率降至最低。Objective Investigate adverse drug reactions （ADR） and the occurrence of the general rules of the factors and characteristics, Thus provide the basis for clinical use of drugs and medication safety. Methods 2012-2013 collected 127 cases of adverse drug reaction reports for analysis, According to the route of administration of drugs, drug type, ADR extent, ADR and the organ systems involved in doing analysis and other clinical manifestations.Results The study involved 127 CPC drugs, Wherein the antimicrobial drugs in the first place, Followed by medicine; Caused due to intravenous ADR121 cases, Accounting for 95.3%; DAR can occur in the human body every system and organ, Can be expressed as allergy, The most serious skin damage, Followed by nervous system damage.Conclusion Monitoring efforts should strengthen the case for the DAR, ADR-related knowledge and conduct outreach, Clinical rational drug use, Try to minimize the incidence of DAR.

关 键 词：药物不良反应 报告 分析 

分 类 号：R91[医药卫生—药学]