2012年理塘县人间鼠疫调查结果分析  

Study of Human Plague in Li Tang County in 2012

作　　者：段勇军[1] 李伟[1] 汪立茂[2] 刘伦光[2] 李帆[2] 何前军[1] 段凤刚[1] 杨军[1] 刀吉 祁腾[2] 

机构地区：[1]甘孜州疾病预防控制中心,四川康定626000 [2]四川省疾病预防控制中心,四川成都610041 [3]理塘县疾病预防控制中心,四川理塘624300

出　　处：《现代预防医学》2015年第2期332-334,共3页Modern Preventive Medicine

基　　金：四川省卫生厅科研课题(130526)

摘　　要：目的分析2012年理塘县人间鼠疫疫情,为人间鼠疫处置提供科学依据。方法运用流行病学调查方法,并结合临床表现和实验室检测结果。结果从死者的右腋下淋巴穿刺液、右腋下淋巴结、肋骨和皮下血棉拭子分离出鼠疫菌;自毙喜马拉雅旱獭股骨分离出鼠疫菌;IHA检测血清52份,结果均为阴性;RIHA检测人体及旱獭标本悬液10份,阳性8份,最高滴度为1∶40 960。结论通过流行病学调查、临床表现和实验室检测结果,确认死者是感染鼠疫菌而引起腺鼠疫继发败血型鼠疫导致死亡;在自毙旱獭分离出鼠疫菌确定理塘县为鼠疫自然疫源地,动物鼠疫流行猛烈,人间鼠疫和动物间鼠疫并发。Objective This work was to investigate the human plague in Litang County in 2012, and to provide scientific foundation for coping with human plague. Methods Epidemiological survey, observation of clinical manifestation and laboratory test were combined to investigate the human plague. Results Y. pestis was isolated from right lymphatic puncture liquid, right axillary lymph nodes, frame, and subcutaneous blood cotton swab of the defunct. One Y. pestis isolate was from a dead Marmota himalayana.Indirect hemagglutination test（IHA） was conducted to 52 serum samples and all were negative. Reverse indirect hemagglutination test（RIHA） was conducted to 10 suspension of samples from human and Marmota himalayana. Among them, eight samples were positive. The highest titer was 1：40960. Conclusion According to the epidemiological investigation, clinical manifestation and laboratory test, the death reason of the defunct was the infection of Y. Pestis. Litang county is the natural foci of plague because Y.Pestis was isolated from Marmota himalayana. Serious plague epidemic among human being and animals took place at the same time at Litang County in 2012.

关 键 词：理塘县 人间鼠疫 鼠疫自然疫源地 

分 类 号：R183.7[医药卫生—流行病学]