滋肾养肝健脾法治疗原发性干燥综合征36例  

Primary sjogren's syndrome treated by Zishen Yanggan Jianpi decoction

作　　者：安琦[1] 丁井永[1] 刘莉君 吕婷婷[1] 马飞燕[1] 余咏[1] 

机构地区：[1]第四军医大学唐都医院,西安710038 [2]陕西省中医医院,西安710003

出　　处：《陕西中医》2015年第1期29-31,共3页Shaanxi Journal of Traditional Chinese Medicine

摘　　要：目的:观察滋肾养肝健脾法治疗原发性干燥综合征的临床疗效。方法:将68例患者随机分为对照组(32例)和治疗组(36例),对照组予以羟氯喹,治疗组予羟氯喹和滋肾养肝健脾中药汤剂,两组患者疗程均为3个月。结果:治疗后两组口眼干燥、关节疼痛、滤纸试验及实验室指标较治疗前均有明显改善(P<0.05,P<0.01),且治疗组明显优于对照组(P<0.01);两组治疗后有效率及不良反应率分别是:对照组为63.63%和27.27%、治疗组为96.15%和3.85%,两组比较均有显著性差异(P<0.01)。结论:滋肾养肝健脾法治疗原发性干燥综合征可明显改善症状、提高临床疗效、降低不良反应的发生。Objective：To observe the clinical effects for therapy of Zishen Yanggan Jianpi Decoction in the treat‐ment for primary Sjogren’s Syndrome（pSS） .Methods ：68 patients were randomly divided into the control group （32 ca‐ses） ,which were only administered with hydroxychloroquine ,and the treatment group （36 cases） that were treated with hydroxychloroquine combined with Zishen Yanggan Jianpi Decoction .Two of the interventions lasted for three months . Results ：Compared with that before treatment ,the symptoms ,signs and laboratory indexes were significantly improved after treatment in both groups （P〈0 .05 ,P〈0 .01） .And the treatment group was superior to the control one （P〈0 . 01） .Furthermore the total effective rate and adverse reaction were significant differences between the two groups ,which were respectively 63 .63% and 27 .27% in the control group ,while 96 .15% and 3 .85% in the treatment group .Conclu‐sions ：The treatment group that supplied hydroxychloroquine combined with Zishen Yanggan Jianpi Decoction can amelio‐rate the symptoms of the patients ,improve clinical efficacy and decrease adverse reactions .

关 键 词：干燥综合征/中医药疗法 六味地黄丸/治疗应用 

分 类 号：R593.2[医药卫生—内科学]