水通道蛋白在羊水量异常调节机制中的地位  

Study on the Significance of Aquaporins in the Regulation of Amniotic Fluid Volume Disorder

作　　者：石小芳[1] 卢仙明 崔燕[1] 柴成良[1] 王俊青[3] 王晓慧[1] 

机构地区：[1]兰州大学第一医院妇产科,兰州730000 [2]青海大学附属医院泌尿外科,西宁810000 [3]解放军第五三六医院妇产科,西宁810000

出　　处：《医学综述》2015年第1期18-20,共3页Medical Recapitulate

基　　金：甘肃省自然科学基金(2060203)

摘　　要：羊水是胎儿赖以生存、发育的环境,羊水量异常严重威胁着胎儿在子宫内的安危。近年来关于水通道蛋白(AQP)与羊水量调节的研究引起了重视,尤其是AQP-1、-3、-8、-9、-11的特点及其在胎盘胎膜的表达。该文通过回顾羊水量异常与AQP之间的相关性研究,旨在发现AQP家族在胎盘的分布及其随羊水量变化表达程度的变化,为羊水量异常的机制及治疗提供新的思路。Amniotic fluid is essential for fetal growth and development,rod amniotic fluid volume disorder is a serious threat to the fetus.In recent years,research on the relationship between aquaporins and regulation of amniotic fluid volume disorder has been valued,especially study on the characteristics of five AQPs [AQP1,3,8,9 and 11] and their expression in placenta and fetal membranes.Here is to make a review of the correlation between aquaporins and amniotic fluid volume disorder,in order to find the distribution of aquaporins and the change of its expression along with the change of amniotic fluid volume,and provide new ideas in the exploring the mechanism and treatment of amniotic fluid volume disorder.

关 键 词：水通道蛋白 羊水过多 羊水过少 

分 类 号：R714.7[医药卫生—妇产科学]