新生儿脐血IgE阳性与父母过敏史及出生情况的关系  

Relationship between neonatal cord blood Ig E positiveness and their parents allergies as well as birth status

作　　者：王海莲[1] 王美英[1] 王仲安[1] 昌晓军[1] 王莉钦 

机构地区：[1]浙江省杭州市余杭区妇幼保健院,浙江杭州311100

出　　处：《上海预防医学》2015年第1期24-26,共3页Shanghai Journal of Preventive Medicine

基　　金：浙江省医药卫生科技计划项目(2012KYA166号)

摘　　要：[目的]探讨新生儿脐血IgE阳性与父母过敏史及出生情况的关系。[方法]对临产孕妇进行问卷调查及血清25-羟维生素D3检测,并采集脐血检测IgE,跟踪新生儿记录出生情况,分析脐血IgE值的相关因素。[结果]母亲有过敏性疾病史、新生儿出生时体重过大、男性及出生时窒息史等与脐血IgE阳性有相关性(OR=1.65、3.36、1.90和2.88,P<0.05)。[结论]母亲有过敏史是脐血IgE升高的危险因素,应做好母亲有过敏史婴儿的湿疹防治工作。Objective To explore the relationship between neonatal cord blood IgE value and their parents allergies as well as birth status . [ Methods ] The pregnant women in labor were investigated by questionnaire and detected for blood 25-hydroxy vitamin D3 .The neonatal cord blood was collected for detection of IgE in childbirth , and the birth status was traced and recorded .Statistical analysis was done on the correlative factors of umbilical cord blood IgE . [ Results] The facts that mother had history of allergic diseases（OR=1.65）, neonatal birth weight was too large （OR=3.36）, baby was male （OR=1.90）, and born with asphyxia （OR=2.88） were all associated with the positiveness of cord blood IgE （P＆lt;0.05）. [Conclusion] The allergy history of mother is a risk factor for the rise of cord blood IgE, so measures for eczema prevention should be well taken for her baby .

关 键 词：脐血IGE 过敏 新生儿 出生情况 

分 类 号：R174[医药卫生—妇幼卫生保健]