蛆虫清创疗法在难愈性感染创面的临床应用  

The Clinical Application of Maggot Debridement Therapy in the Refractory Infectious Wound

作　　者：夏效泳[1] 范媛媛[2] 史宗新[1] 于远洋[1] 孔祥禄[1] 王江宁[3] 

机构地区：[1]首都医科大学良乡教学医院,北京102401 [2]北京大学第一医院,北京100034 [3]首都医科大学附属世纪坛医院,北京100038

出　　处：《现代生物医学进展》2014年第36期7186-7189,共4页Progress in Modern Biomedicine

摘　　要：蛆虫治疗感染创面已有近千年的历史,始载于《本草纲目》,具有良好的疗效。20世纪40年代以后,随着抗生素的广泛使用,蛆虫治疗感染创面的方法逐渐被遗弃。但是随着抗生素的滥用,以及细菌严重耐药性的出现,使得人们开始重新审视这种古老而又充满生机的方法。在难愈性感染创面的治疗过程中,蛆虫通过多种作用机制能够促进创面的愈合,清除大量的坏死组织,促进肉芽组织生长,并有显著的抑菌作用。蛆虫通过多种作用机制协同作用能够促进难愈性感染伤口的愈合,值得进一步的临床研究及推广。本文广泛查阅近年国内外相关文献进行回顾与综合分析。对蛆虫清创疗法在难愈性感染创面的临床应用进行综述。Treating infected wounds by maggot, which has a history of nearly one thousand years, was first recorded by the《Compendium of Materia Medica》, and it had good treatment effect. Since the nineteen forties, with the widespread use of antibiotics,the maggot therapy for infected wounds was gradually abandoned. But with the abuse of antibiotics, and the emergence of serious bacterial drug resistance, people began to re-examine this methods which was ancient but full of vitality. In the course of the treatment of refractory infected wound, maggots could promote wound healing by a variety of mechanisms, clear a lot of necrotic tissue, and promote the growth of granulation tissue, and they have a significant inhibitory effect. Maggots could promote the healing of refractory infected wounds by multiple mechanisms of synergy, and be worthy of further clinical research and promotion.The related biomedical research materials at home and broad were consulted and analyzed to introduce the mechanism of the maggot debridement therapy in the refractory infected wounds.

关 键 词：难愈性创面 创面修复 蛆虫清创疗法 作用机制 

分 类 号：R282.74[医药卫生—中药学] R632.1[医药卫生—中医学]