1599例前列腺液标本支原体感染检测及药敏结果分析  

Detection of mycoplasma from prostatic fluid in 1599 patients and their antibiotic susceptibilities study

作　　者：周兴[1] 何清湖[2] 周青[1] 朱惠斌[3] 

机构地区：[1]湖南中医药大学第一附属医院男性病科,长沙410007 [2]湖南中医药大学,长沙410208 [3]湖南中医药大学第一附属医院检验科,长沙410007

出　　处：《中国性科学》2014年第12期9-11,共3页Chinese Journal of Human Sexuality

基　　金：国家自然科学基金(81373641;81202706)

摘　　要：目的:回顾本地区男性泌尿生殖道患者感染解脲支原体(UU)、人型支原体(MH)的分布状况,了解支原体对12种抗生素体外药物敏感试验的现状。方法:对1599例男性泌尿生殖道感染患者前列腺液标本进行支原体(Uu、MH)培养及药敏试验。结果:1599例检测标本中,总感染率为23.08%,单纯UU阳性277例(75.07%),UU-Mh阳性81例(21.95%),单纯Mh阳性11例(2.98%)。MH对强力霉素(DOX)、交沙霉素(JOS)、美满霉素(MIN)全部敏感,UU对JOS、MIN、DOX、环酯红霉素(ECC)、克拉霉素(CLA)均非常敏感,UU-MH混合感染的耐药率明显高于单纯UU或MH感染。结论:临床治疗支原体感染时应尽量根据药敏结果选择敏感药物,DOX、MIN和JOS可作为本地区临床经验用药的首选药物。Objectives：To review the incidences of urogenital tract infection caused by ureaplasma urealyti-cum （UU）and mycoplasma hominis （MH）and their susceptibilities to 12 antibiotic agents.Methods：UU and MH were cultured and their drug susceptibilities from 1 ,599 patients with urogenital tract infections were statistically analyzed.Results：The overall positive incidence of gential mycoplasmas was 23.08%.The most common pattern was UU mono-infection （75.07%）;the UU-MH co-infection pattern ranked second （21.95%）and MH mono-infection was lowest （2.98%）.However,a significantly higher infection rate by genital mycoplasmas was found in young men （age range：21 -50 years）.Overall,MH complete susceptibility to doxycycline （DOX）,josamycin （JOS）and minocycline （MIN）,while UU had high susceptibility rates to JOS,MIN,DOX,erythromycin cyclocar-bonate （ECC）and clarithromycin （CLA）.The resistance rates of UU-MH-mixed isolates to most of drugs were significantly higher than those of UU-or MH-single isolates.Conclusions：The laboratory screening and antimi-crobial susceptibility testing for genital mycoplasmas is vital to treat the infection.According to the empirical treat-ment of mycoplasma infection,DOX,MIN,and JOS can be taken as the drugs of first choice.

关 键 词：男性 解脲支原体 人型支原体 药物敏感性实验 

分 类 号：R167[医药卫生—公共卫生与预防医学]