脂氧素的抗炎镇痛与神经保护作用研究进展  

The Advances of Lipoxins in Anti-inflammation,Analgesia and Neuroprotection

作　　者：胡珊[1] 王志福[1] 田瑜[1] 王彦青[1] 

机构地区：[1]复旦大学基础医学院中西医结合学系,针刺原理研究所,医学神经生物学国家重点实验室,上海200032

出　　处：《中国细胞生物学学报》2014年第12期1601-1608,共8页Chinese Journal of Cell Biology

基　　金：国家自然科学基金(批准号:30970975)资助的课题~~

摘　　要：脂氧素是一类来源于花生四烯酸具有抗炎和促炎症消退的脂类介质。作为炎症过程中的负性调控因子,被广泛用于治疗各种急慢性炎症、疼痛、脑血管疾病及各种恶性肿瘤。该文将就其在抗炎镇痛和神经保护方面的研究进展作一综述。Lipoxins are lipid mediators generated from arachidonic acid that act to anti-inflammation and promote resolution. Lipoxins have emerged as potential anti-inflammatory mediators that be used in various inflam- mation, chronic pain, cere-brovascular diseases and malignant tumors. In this review, we briefly outline the recent research advances of Lipoxins in inflammation, analgesia and neuroprotection.

关 键 词：脂氧素 炎症 镇痛 

分 类 号：R965[医药卫生—药理学]