山茱萸连续超声逆流提取工艺研究  被引量:1

Successive Ultrasound Countercurrent Extraction of Cornus Officinalis

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作  者:盖晓华[1] 王青[1] 李炳超[1] 赵爱丽[1] 王燕臣 王晓南[1] 

机构地区:[1]石家庄以岭药业股份有限公司,河北石家庄050035

出  处:《中医药学报》2014年第6期38-40,共3页Acta Chinese Medicine and Pharmacology

基  金:国家"十二五"重大新药创制(2011ZX09401-306)

摘  要:目的:优化山茱萸连续超声逆流的提取工艺。方法:以提取物中干膏收率和马钱苷转移率为考察指标,采用山茱萸连续超声逆流提取工艺参数进行考察。结果:山茱萸连续超声逆流的提取工艺最佳条件是药材不需要粉碎,超声频率30k Hz,80%乙醇,料液流量比1∶15。结论:优选连续超声逆流提取工艺操作简单、科学合理,适合工业化大生产。Objective: To optimize the successive ultrasound countercurrent extraction from Cornus officinalis. Method:Take the rate of dry extract and transport rate of loganin as assessment index and use orthogonal test to optimize the successive ultrasound countercurrent extraction parameter of Cornus officinalis. Result: The optimum extraction condition was that herbs needn't be crushed Ultrasound frequency was 30 k Hz,and the solvent was 80% alcohol. The ratio of feed to solvent was 1∶ 15. Conclusion: The optimum extraction technology is reasonable and scientific,and it could be used for large scale production.

关 键 词:山茱萸 连续超声逆流 马钱苷 正交试验 

分 类 号:R284.2[医药卫生—中药学]

 

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