基于MR成像布-加综合征血流动力学数值模拟分析  

Numerical simulation analysis of hemodynamic values of budd-chiari syndrome based on MR image

作　　者：孙存杰[1] 赵英红[2] 平杰[1] 崔艳峰[3] 

机构地区：[1]徐州医学院附属医院影像科 [2]徐州医学院医学影像学院,徐州221004 [3]徐州医学院附属医院介入放射科,徐州221006

出　　处：《医学研究生学报》2014年第12期1297-1300,共4页Journal of Medical Postgraduates

基　　金：徐州市科技项目(XM12B011)

摘　　要：目的布-加综合征(Budd-Chiari syndrome,BCS)的血流动力学机制是近年来的研究热点。本研究应用计算流体力学(computational fluid dynamics,CFD)方法对BCS患者的下腔静脉进行三维数值模拟,探讨其血流动力学特性。方法采用Ansys软件对布-加综合征患者的MR图像进行三维重建,构建下腔静脉个体化三维模型;利用计算流体力学方法对该模型进行数值模拟计算。结果精确仿真下腔静脉三维流体模型,在功能上该模型成功演示了布-加综合征患者下腔静脉血流动力学环境变化过程。病变区域上方有涡流产生;冠状面模拟显示狭窄处血流流速急升高;在狭窄端入口处至最狭窄处静压值逐渐下降,至狭窄处出口处最低;狭窄处的壁面切应力值达到最大。结论该特征性三维血流动力学模型能真实的进行体外模拟布-加综合征的血流动力学特征,血流动力学参量分析结果符合临床实际,有助于进一步研究下腔静脉血管形态病变与复杂血流动力学参数之间的相关性。Objective The hemodynamic mechanism of Budd-Chiari syndrome （BCS） has become the research hotspot in recent years. The aim of this study was to discuss the hemodynamie characteristics of BCS through 3D numerical simulation for inferior vena eava stenosis based on the fluid dynamics （CFD） method. Methods 3D model was established from a patient with Budd- Chiari syndrome based on MR image with Ansys software. The numerical simulation of this model was performed by the CFD. Results The 3D model of inferior vena eava functionally demonstrated the change procedure of hemodynamie characteristics of BCS. Vortex was found above the narrow area, and blood flow velocity achieved maximum in the center of the stenosis throughout the coronal section graph. The static pressure value gradually declined at the narrow area entrance to the narrowest place, and achieved minimum value at the exit. The maximum wall shear stress existed in the stenosis. Conclusion Specific 3D computational hemodynamic model can show the hemodynamic characteristics of BCS, and its hemodynamic parameters could be used for clinical practice. It will facilitate the study on correlation of complex hemodynamie parameters and morphology changes of inferior vena eava vascular.

关 键 词：布-加综合征 计算流体力学 血流动力学 

分 类 号：R657.3[医药卫生—外科学]