iVue OCT扫描品质指数与白内障患者眼底像模糊程度的相关性  

Association of iVue OCT Signal Strength Index with blur degree of fundus photographs in cataracts

作　　者：张景尚[1,2,3] 王进达[1,2,3] 万修华[1,2,3] 安莹[1,2,3] 苏炳男[1,2,3] 徐亮[1,2,3] 李建军[1,2,3] 

机构地区：[1]首都医科大学附属北京同仁医院 [2]北京同仁眼科中心 [3]北京市眼科研究所 眼科学与视觉科学北京市重点实验室,100005

出　　处：《眼科》2014年第6期398-401,共4页Ophthalmology in China

基　　金：北京市科技新星项目(z131102000413025);国家科技支撑计划课题(2013BAH19F04;2012BAH05F05)

摘　　要：目的分析iVue OCT扫描品质指数与白内障眼底像模糊程度的相关性,探讨用该指数评价白内障程度的可行性。设计诊断方法评价。研究对象2013年北京同仁医院眼科门诊的白内障患者162例（324眼）。方法所有患者均经裂隙灯显微镜检查确定有无白内障。使用免散瞳眼底数码照相机进行眼底数码照相及外眼数码照相检查,根据眼底像的模糊程度分级（1~5级）;根据外眼像获取瞳孔直径与角膜直径的比值。使用iVue OCT检查获取黄斑结构图像以及扫描品质指数并分为高、中、低三级,分析iVue OCT扫描品质指数与白内障眼底像模糊程度相关性,并分析该评价方法的灵敏度及特异度。主要指标眼底像模糊程度分级、OCT扫描品质指数分级、特异度、灵敏度。结果随着眼底像模糊程度的增加,iVue OCT扫描品质指数值不断减小（r=0.891,P〈0.001）。高iVue OCT扫描品质指数评价0级白内障眼底像模糊程度的灵敏度为89%,特异度为78%;中度iVue OCT扫描品质指数评价2级白内障眼底像模糊程度的灵敏度为88%,特异度为67%;低iVue OCT扫描品质指数评价4级白内障眼底像模糊程度的灵敏度为100%,特异度为94%。瞳孔大小与iVue OCT扫描品质指数之间无相关性（P=0.989）。结论 iVue OCT扫描品质指数与白内障眼底像模糊程度具有较好的相关性,对于轻度和重度白内障用iVue OCT扫描品质指数可以准确评价白内障眼底像模糊程度。Objective To analyze the association of the iVue OCT Signal Strength Index with the blur degree of fundus pho- tographs in cataracts and to explore the feasibility to evaluate the severity of the cataract using the index. Design Evaluation of diag- nostic methods. Participants 162 patients （324 eyes） with cataract at Beijing Tongren Hospital in 2013. Methods All cases were con- firmed by slit-lamp microscope examination. Eundus photographs and anterior segment photographs were taken with the non-mydriatie fundus digital camera. The grade of fundus photographs was based on the blur degree. The ratio of the diameter of the pupil and corneal diameter was obtained according to anterior segment photographs. The Signal Strength Index was obtained by the iVue OCT. Main Outcome Measures The grade of fundus photographs, the grade of the Signal Strength Index, sensitivity, and specificity. Results With the increasing of the fundus photographs blur degree, the Signal Strength Index of iVue OCT decreased （r=0.891, P〈0.001）. The sensi- tivity of high Signal Strength Index evaluating the 0 degree of cataract fundus photographs was 89% and the specificity was 78%. The sensitivity of the moderate Signal Strength Index evaluating the 2 degree of cataract fundus photographs was 88% and the specificity was 67%. The sensitivity of the low Signal Strength Index evaluating the 4 degree of cataract fundus photographs was 100% and the specificity was 94%. There is no significant correlation between pupil size and the Signal Strength Index （P=0.989）. Conclusion The Signal Strength Index and the blur degree of fundus image in cataract have a good correlation. The Signal Strength Index of iVue OCT could accurately evaluate the blur degree of fundus photographs in the mild and severe cataracts.

关 键 词：白内障 iVue OCT 扫描品质指数 眼底像模糊程度 

分 类 号：R776.1[医药卫生—眼科]